The recommended approach to the increased risk of colorectal carcinoma in ulcerative colitis
has been colonoscopic surveillance rather than prophylactic colectomy. This strategy is …

Background: There is an impression mostly from specialty clinics that patients with inflammatory
bowel disease (IBD) have an increased risk of venous thromboembolic disorders. Our …

Psycho-neuro-endocrine-immune modulation through the brain-gut axis likely has a key
role in the pathogenesis of inflammatory bowel disease (IBD). The brain-gut axis involves …

The human endogenous intestinal microflora is an essential “organ” in providing nourishment,
regulating epithelial development, and instructing innate immunity; yet, surprisingly, basic …

The discovery of a series of genetic and serological markers associated with disease
susceptibility and phenotype in inflammatory bowel disease has led to the prospect of an …

Background Infliximab, a monoclonal antibody against tumor necrosis factor, is an effective
maintenance therapy for patients with Crohn's disease without fistulas. It is not known …

BACKGROUND The objective of the current study was to determine the incidence of cancer
among persons with inflammatory bowel disease (IBD) and to compare these incidence …

OBJECTIVE: The aim of this study was to determine the prevalence of the major extraintestinal
manifestations of inflammatory bowel disease (IBD) and their relation to disease …

BACKGROUND Previously, we have demonstrated a high incidence and prevalence of Crohn's
disease (CD) and ulcerative colitis (UC) in the Canadian province of Manitoba. However…

The aim of this study was to assess the accuracy and utility of administrative health data in
identifying persons with inflammatory bowel disease on a population basis and to determine …