Objective To develop a new evidence‐based, pharmacologic treatment guideline for rheumatoid
arthritis (RA). Methods We conducted systematic reviews to synthesize the evidence for …

Sex-related influences on pain and analgesia have become a topic of tremendous scientific
and clinical interest, especially in the last 10 to 15 years. Members of our research group …

An estimated 2·6 million third trimester stillbirths occurred in 2015 (uncertainty range 2·4–3·0
million). The number of stillbirths has reduced more slowly than has maternal mortality or …

Background We update recommendations on 12 topics that were in the 9th edition of these
guidelines, and address 3 new topics. Methods We generate strong (Grade 1) and weak (…

To evaluate the role of oncogenic RAS mutations in pancreatic tumorigenesis, we directed
endogenous expression of KRAS G12D to progenitor cells of the mouse pancreas. We find …

… The tephra has been dated at several sites in the area to about 25,300 radiocarbon ( 14 C)
years bp, or about 30,000 calendar years 10,12 . The cryostratigraphic context is similar to …

… Hepatitis B or C. The panel recommends that etanercept could potentially be used in RA
patients with hepatitis C requiring RA treatment (Table 4). The panel also recommends not …

Objective To provide guidance for the management of gout, including indications for and
optimal use of urate‐lowering therapy ( ULT ), treatment of gout flares, and lifestyle and other …

Human schistosomiasis—or bilharzia—is a parasitic disease caused by trematode flukes of
the genus Schistosoma. By conservative estimates, at least 230 million people worldwide …

The cellular gene encoding the receptor for epidermal growth factor (EGF) has considerable
homology to the oncogene of avian erythroblastosis virus. In a human mammary carcinoma, …