Neuron number and size in prefrontal cortex of children with autism

…, C Ahrens-Barbeau, MJ Hallet, CC Barnes… - Jama, 2011 - jamanetwork.com
Context Autism often involves early brain overgrowth, including the prefrontal cortex (PFC).
Although prefrontal abnormality has been theorized to underlie some autistic symptoms, the …

Longitudinal magnetic resonance imaging study of cortical development through early childhood in autism

CM Schumann, CS Bloss, CC Barnes… - Journal of …, 2010 - Soc Neuroscience
Cross-sectional magnetic resonance imaging (MRI) studies have long hypothesized that the
brain in children with autism undergoes an abnormal growth trajectory that includes a …

Amygdala enlargement in toddlers with autism related to severity of social and communication impairments

CM Schumann, CC Barnes, C Lord, E Courchesne - Biological psychiatry, 2009 - Elsevier
BACKGROUND: Autism is a heterogeneous neurodevelopmental disorder of unknown etiology.
The amygdala has long been a site of intense interest in the search for neuropathology …

Altered proliferation and networks in neural cells derived from idiopathic autistic individuals

…, L Eichenfield, T Pramparo, LT Eyler, CC Barnes… - Molecular …, 2017 - nature.com
Autism spectrum disorders (ASD) are common, complex and heterogeneous neurodevelopmental
disorders. Cellular and molecular mechanisms responsible for ASD pathogenesis …

Evaluation of the diagnostic stability of the early autism spectrum disorder phenotype in the general population starting at 12 months

K Pierce, VH Gazestani, E Bacon, CC Barnes… - JAMA …, 2019 - jamanetwork.com
Importance Universal early screening for autism spectrum disorder (ASD) in primary care is
becoming increasingly common and is believed to be a pivotal step toward early treatment. …

[HTML][HTML] Eye tracking reveals abnormal visual preference for geometric images as an early biomarker of an autism spectrum disorder subtype associated with …

…, S Marinero, R Hazin, B McKenna, CC Barnes… - Biological …, 2016 - Elsevier
Background Clinically and biologically, autism spectrum disorder (ASD) is heterogeneous.
Unusual patterns of visual preference as indexed by eye tracking are hallmarks; however, …

Measurement of quality of life in end-stage renal disease: the time trade-off approach.

…, GW Torrance, DW Taylor, CC Barnes… - … . Medecine clinique et …, 1987 - europepmc.org
The quality of life of patients with end-stage renal disease was estimated using the time
trade-off technique. The sample included 103 transplant, 60 hospital hemodialysis, 57 home/self-…

[HTML][HTML] Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages

ML Chow, T Pramparo, ME Winn, CC Barnes… - PLoS …, 2012 - journals.plos.org
Autism is a highly heritable neurodevelopmental disorder, yet the genetic underpinnings of
the disorder are largely unknown. Aberrant brain overgrowth is a well-replicated observation …

[PDF][PDF] Different functional neural substrates for good and poor language outcome in autism

MV Lombardo, K Pierce, LT Eyler, CC Barnes… - Neuron, 2015 - cell.com
Autism (ASD) is vastly heterogeneous, particularly in early language development. While ASD
language trajectories in the first years of life are highly unstable, by early childhood these …

[HTML][HTML] Diffusion tensor imaging provides evidence of possible axonal overconnectivity in frontal lobes in autism spectrum disorder toddlers

…, K Campbell, V Venkatraman, CC Barnes… - Biological …, 2016 - Elsevier
Background Theories of brain abnormality in autism spectrum disorder (ASD) have focused
on underconnectivity as an explanation for social, language, and behavioral deficits but are …