User profiles for Bruce G. Pollock

Bruce G.Pollock

Professor of Psychiatry and Pharmacology, Unitvrsity of Toronto
Verified email at camh.ca
Cited by 36403

Mood disorders in the medically ill: scientific review and recommendations

…, D Musselman, C O'Connor, JM Petitto, BG Pollock… - Biological …, 2005 - Elsevier
OBJECTIVE: The purpose of this review is to assess the relationship between mood disorders
and development, course, and associated morbidity and mortality of selected medical …

Nortriptyline and interpersonal psychotherapy as maintenance therapies for recurrent major depression: a randomized controlled trial in patients older than 59 years

…, PR Houck, MA Dew, JA Stack, BG Pollock… - Jama, 1999 - jamanetwork.com
ContextElderly patients with major depression are at high risk for recurrence, increased
mortality, and chronic disability.ObjectiveTo determine the efficacy of maintenance nortriptyline …

Anticipating and mitigating the impact of the COVID-19 pandemic on Alzheimer's disease and related dementias

EE Brown, S Kumar, TK Rajji, BG Pollock… - The American Journal of …, 2020 - Elsevier
The COVID-19 pandemic is causing global morbidity and mortality, straining health systems,
and disrupting society, putting individuals with Alzheimer's disease and related dementias (…

The anticholinergic drug scale as a measure of drug‐related anticholinergic burden: associations with serum anticholinergic activity

…, BC Lund, PJ Perry, BG Pollock… - The Journal of …, 2006 - Wiley Online Library
Anticholinergic Drug Scale (ADS) scores were previously associated with serum anticholinergic
activity (SAA) in a pilot study. To replicate these results, the association between ADS …

The nature and determinants of neuropsychological functioning in late-lifedepression

…, R Bhalla, CC Meltzer, BG Pollock… - Archives of general …, 2004 - jamanetwork.com
… After verifying that there were no interactions betweengroup and CIRS-G total score, we
used multivariate analysis of covariance(MANCOVA) to model the main effect of group on the 5 …

Serotonin in aging, late-life depression, and Alzheimer's disease: the emerging role of functional imaging

CC Meltzer, G Smith, ST DeKosky, BG Pollock… - …, 1998 - Elsevier
Serotonin (5-HT) neuron and neurotransmitter loss in normal aging and neuropsychiatric
diseases of late life may contribute to behavioral changes commonly observed in the elderly …

Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life

…, J Pearson, T Persky, BG Pollock… - Archives of general …, 2003 - jamanetwork.com
Objectives To review progress made during the past decade in late-life mood disorders and
to identify areas of unmet need in health care delivery and research. Participants The …

Anticholinergic activity of 107 medications commonly used by older adults

ML Chew, BH Mulsant, BG Pollock… - Journal of the …, 2008 - Wiley Online Library
The objective of this study was to measure the anticholinergic activity (AA) of medications
commonly used by older adults. A radioreceptor assay was used to investigate the AA of 107 …

Newer antidepressants and the cytochrome P450 system.

CB Nemeroff, CL DeVane, BG Pollock - The American journal of …, 1996 - europepmc.org
Objective This review evaluates the in vitro and in vivo evidence for inhibition of cytochrome
P450 enzymes by the newer antidepressants and provides clinical recommendations for …

Effect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial

AP Porsteinsson, LT Drye, BG Pollock, DP Devanand… - Jama, 2014 - jamanetwork.com
Importance Agitation is common, persistent, and associated with adverse consequences for
patients with Alzheimer disease. Pharmacological treatment options, including …