Objective: To update and expand the 2013 Clinical Practice Guidelines for the Management
of Pain, Agitation, and Delirium in Adult Patients in the ICU. Design:

Background: Venous thromboembolism (VTE) complicates ∼1.2 of every 1000 deliveries.
Despite these low absolute risks, pregnancy-associated VTE is a leading cause of maternal …

Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

Purpose Targeted temperature management (TTM) may improve survival and functional
outcome in comatose survivors of out-of-hospital cardiac arrest (OHCA), though the optimal …

Importance Endovascular intervention for acute ischemic stroke improves revascularization.
But trials examining endovascular therapy yielded variable functional outcomes, and the …

Objective To compare the effects of treatments for coronavirus disease 2019 (covid-19).
Design Living systematic review and network meta-analysis. Data sources WHO covid-19 …

Noninvasive mechanical ventilation (NIV) is widely used in the acute care setting for acute
respiratory failure (ARF) across a variety of aetiologies. This document provides European …

Background: This document updates the American Thoracic Society/European Respiratory
Society/Japanese Respiratory Society/Latin American Thoracic Association guideline on …

This living guideline by Arnav Agarwal and colleagues (BMJ 2020; 370: m3379, doi: 10.1136/bmj.
m3379) was last updated on 22 April 2022, but the infographic contained two dosing …

Background Studies that have evaluated the use of intravenous vitamin C in adults with
sepsis who were receiving vasopressor therapy in the intensive care unit (ICU) have shown …