Genetic research has moved from Mendelian genetics to sequence maps to the study of
natural human genetic variation at the level of the genome. This past decade of discovery has …

Numerous studies of genetic epidemiology and post-genomics in respiratory diseases rely
on the use of biobanks, defined as organised biological sample collections with associated …

The American College of Medical Genetics and Genomics recently issued recommendations
for reporting incidental findings from clinical whole-genome sequencing and whole-exome …

The last decade has witnessed the emergence of international ethics guidelines discussing
the importance of disclosing global and also, in certain circumstances, individual genetic …

… Bartha Maria Knoppers, … Knoppers BM, Chadwick R (2005) Human genetic research:
Emerging trends in ethics. Nat Rev Genet 6: 75–79. …

1. Purpose The purpose of this Framework is to provide a principled and practical framework
for the responsible sharing of genomic and health-related data. Its primary goals are to: i. …

Biobanks can have a pivotal role in elucidating disease etiology, translation, and advancing
public health. However, meeting these challenges hinges on a critical shift in the way …

Genetic testing based on whole-genome sequencing (WGS) often returns results that are
not directly clinically actionable as well as raising the possibility of incidental (secondary) …

This article describes how the Canadian Health Measures Survey (CHMS) of Statistics
Canada has addressed the ethical, legal and social issues (ELSI) arising from the survey. The …

Early detection of breast cancer through screening reduces breast cancer mortality. The
benefits of screening must also be considered within the context of potential harms (eg, false …