Changes in human DNA methylation patterns are an important feature of cancer development
and progression and a potential role in other conditions such as atherosclerosis and …

The larger RNA segment of infectious bursal disease virus (IBDV:Australian strain 002–73)
has been characterized by cDNA cloning and nucleotide sequence analysis. We believe …

Engineered antibodies and their fragments are invaluable tools for a vast range of biotechnological
and pharmaceutical applications. However, they are facing increasing competition …

Recombinant antibody fragments can be engineered to assemble into stable multimeric
oligomers of high binding avidity and specificity to a wide range of target antigens and haptens. …

In this study, human T cells were provided with a reactivity against the Lewis-Y (Le Y )
carbohydrate antigen, which is overexpressed on 70% of epithelial-derived tumors, but not …

Background: primary and secondary insomnia, especially among older adults, is frequently
encountered by family physicians. Pharmacological interventions, although effective in some …

Diabodies (scFv dimers) are small, bivalent antibody mimetics of approximately 55kDa in
size that possess rapid in vivo targeting pharmacokinetics compared to the intact parent …

We have constructed a temperature-inducible Escherichia coli expression vector (pPOW)
for enhanced secretion of antibody (Ab) domains and other foreign proteins. The vector …

The authors describe the results of a survey they carried out in 2000 to determine the status
of cultural sensitivity training in 16 Canadian medical schools using structured telephone …

The variable heavy (VH) and variable light (VL) genes of NC10, a monoclonal antibody with
specificity toward N9 neuraminidase (NA), were cloned and sequenced. A single chain Fv (…