DNA hypomethylation and human diseases
AS Wilson, BE Power, PL Molloy - … et Biophysica Acta (BBA)-Reviews on …, 2007 - Elsevier
Changes in human DNA methylation patterns are an important feature of cancer development
and progression and a potential role in other conditions such as atherosclerosis and …
and progression and a potential role in other conditions such as atherosclerosis and …
Genomic structure of tbe large RNA segment of infectious bursal disease virus
PJ Hudson, NM McKern, BE Power… - Nucleic acids …, 1986 - academic.oup.com
The larger RNA segment of infectious bursal disease virus (IBDV:Australian strain 002–73)
has been characterized by cDNA cloning and nucleotide sequence analysis. We believe …
has been characterized by cDNA cloning and nucleotide sequence analysis. We believe …
A new generation of protein display scaffolds for molecular recognition
RJ Hosse, A Rothe, BE Power - Protein Science, 2006 - Wiley Online Library
Engineered antibodies and their fragments are invaluable tools for a vast range of biotechnological
and pharmaceutical applications. However, they are facing increasing competition …
and pharmaceutical applications. However, they are facing increasing competition …
Dimeric and trimeric antibodies: high avidity scFvs for cancer targeting
AA Kortt, O Dolezal, BE Power, PJ Hudson - Biomolecular engineering, 2001 - Elsevier
Recombinant antibody fragments can be engineered to assemble into stable multimeric
oligomers of high binding avidity and specificity to a wide range of target antigens and haptens. …
oligomers of high binding avidity and specificity to a wide range of target antigens and haptens. …
Adoptive transfer of T cells modified with a humanized chimeric receptor gene inhibits growth of Lewis-Y-expressing tumors in mice
…, FE Smyth, GA Cartwright, BE Power… - Proceedings of the …, 2005 - National Acad Sciences
In this study, human T cells were provided with a reactivity against the Lewis-Y (Le Y )
carbohydrate antigen, which is overexpressed on 70% of epithelial-derived tumors, but not …
carbohydrate antigen, which is overexpressed on 70% of epithelial-derived tumors, but not …
Non‐pharmacological management of primary and secondary insomnia among older people: review of assessment tools and treatments
…, N Azad, A Byszewski, FFA Sarazan, B Power - Age and …, 2003 - academic.oup.com
Background: primary and secondary insomnia, especially among older adults, is frequently
encountered by family physicians. Pharmacological interventions, although effective in some …
encountered by family physicians. Pharmacological interventions, although effective in some …
The crystal structure of an anti-CEA scFv diabody assembled from T84. 66 scFvs in VL-to-VH orientation: implications for diabody flexibility
JA Carmichael, BE Power, TPJ Garrett… - Journal of molecular …, 2003 - Elsevier
Diabodies (scFv dimers) are small, bivalent antibody mimetics of approximately 55kDa in
size that possess rapid in vivo targeting pharmacokinetics compared to the intact parent …
size that possess rapid in vivo targeting pharmacokinetics compared to the intact parent …
High-level temperature-induced synthesis of an antibody VH-domain in Escherichia coli using the PelB secretion signal
BE Power, N Ivancic, VR Harley, RG Webster, AA Kortt… - Gene, 1992 - Elsevier
We have constructed a temperature-inducible Escherichia coli expression vector (pPOW)
for enhanced secretion of antibody (Ab) domains and other foreign proteins. The vector …
for enhanced secretion of antibody (Ab) domains and other foreign proteins. The vector …
Cultural sensitivity training in Canadian medical schools
N Azad, B Power, J Dollin, S Chery - Academic Medicine, 2002 - journals.lww.com
The authors describe the results of a survey they carried out in 2000 to determine the status
of cultural sensitivity training in 16 Canadian medical schools using structured telephone …
of cultural sensitivity training in 16 Canadian medical schools using structured telephone …
Recombinant antineuraminidase single chain antibody: expression, characterization, and crystallization in complex with antigen
…, AA Kortt, GG Lilley, BE Power… - Proteins: Structure …, 1993 - Wiley Online Library
The variable heavy (VH) and variable light (VL) genes of NC10, a monoclonal antibody with
specificity toward N9 neuraminidase (NA), were cloned and sequenced. A single chain Fv (…
specificity toward N9 neuraminidase (NA), were cloned and sequenced. A single chain Fv (…