Oxidized LDL-activated platelets induce vascular inflammation
…, K Stellos, BF Krämer, B Bigalke… - … in thrombosis and …, 2010 - thieme-connect.com
… The class B scavenger receptor CD36 binds primarily to thrombospondin[11] and
collagen[12] and triggers platelet activation[13] that lead to platelet hyperreactivity. The lectin-like …
collagen[12] and triggers platelet activation[13] that lead to platelet hyperreactivity. The lectin-like …
Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation
…, M Wydymus, K Göhring, C Zürn, B Bigalke… - European heart …, 2006 - academic.oup.com
Aims To assess whether low response to clopidogrel influences cardiovascular outcome after
coronary stent implantation in a consecutively measured cohort of patients with coronary …
coronary stent implantation in a consecutively measured cohort of patients with coronary …
Platelet-Derived Stromal Cell–Derived Factor-1 Regulates Adhesion and Promotes Differentiation of Human CD34+ Cells to Endothelial Progenitor Cells
…, T Schoenberger, A Gauss, T Geisler, B Bigalke… - Circulation, 2008 - Am Heart Assoc
… B, Mean and SEM of 4 to 10 independent experiments are presented. Application of a 1-way
ANOVA analysis showed significant differences among the different groups (P<0.001). …
ANOVA analysis showed significant differences among the different groups (P<0.001). …
Platelets induce differentiation of human CD34+ progenitor cells into foam cells and endothelial cells
Recruitment of human CD34 + progenitor cells toward vascular lesions and differentiation into
vascular cells has been regarded as a critical initial step in atherosclerosis. Previously we …
vascular cells has been regarded as a critical initial step in atherosclerosis. Previously we …
Platelet-leukocyte interactions in inflammation and atherothrombosis
AE May, H Langer, P Seizer, B Bigalke… - … in thrombosis and …, 2007 - thieme-connect.com
… [19] [35] [36] These activation processes involve the activation of nuclear factor kappa B and
stimulate leukocyte adhesion (upregulation and activation of Mac-1 and very late antigen-4[…
stimulate leukocyte adhesion (upregulation and activation of Mac-1 and very late antigen-4[…
[HTML][HTML] The residual platelet aggregation after deployment of intracoronary stent (PREDICT) score
T Geisler, D Gra, B Bigalke, K Stellos, T Drosch… - Journal of Thrombosis …, 2008 - Elsevier
Background: Recent studies suggest a high interindividual variability of response to
clopidogrel associated with adverse cardiovascular outcome. Different clinical factors are …
clopidogrel associated with adverse cardiovascular outcome. Different clinical factors are …
The MOGE (S) classification for cardiomyopathies: current status and future outlook
…, SE Ludwig, S Mavrogeni, B Bigalke… - Heart Failure …, 2017 - Springer
Cardiomyopathies are complex diseases of multifactorial pathogenesis and have a high
morbidity and mortality. Over the past decades, several revisions of classifications and …
morbidity and mortality. Over the past decades, several revisions of classifications and …
[HTML][HTML] Cardiovascular magnetic resonance feature-tracking assessment of myocardial mechanics: Intervendor agreement and considerations regarding …
…, S Kutty, M Fasshauer, W Staab, JM Sohns, B Bigalke… - Clinical radiology, 2015 - Elsevier
Aim To assess intervendor agreement of cardiovascular magnetic resonance feature tracking
(CMR-FT) and to study the impact of repeated measures on reproducibility. Materials and …
(CMR-FT) and to study the impact of repeated measures on reproducibility. Materials and …
EMMPRIN and its ligand cyclophilin A regulate MT1-MMP, MMP-9 and M-CSF during foam cell formation
…, M Schött, MR Lang, HF Langer, B Bigalke… - Atherosclerosis, 2010 - Elsevier
… (B) Representative zymography of cell culture supernatants of undifferentiated CD34 +
progenitor cells and progenitor cell-derived foam cells. One representative zymography for MMP-…
progenitor cells and progenitor cell-derived foam cells. One representative zymography for MMP-…
Expression of stromal-cell-derived factor-1 on circulating platelets is increased in patients with acute coronary syndrome and correlates with the number of CD34+ …
K Stellos, B Bigalke, H Langer, T Geisler… - European heart …, 2009 - academic.oup.com
… We found that platelet SDF-1 surface expression was significantly enhanced in ACS compared
with SAP (ACS (MFI ± SD): 18.45 ± 12.85; SAP: 13.48 ± 5.27; P < 0.001; Figure 1A and B)…
with SAP (ACS (MFI ± SD): 18.45 ± 12.85; SAP: 13.48 ± 5.27; P < 0.001; Figure 1A and B)…