Objective: The role of intensive insulin therapy in medical surgical intensive care patients
remains unclear. The objective of this study was to examine the effect of intensive insulin …

Background Recent studies have reported a high prevalence of relative adrenal insufficiency
in patients with liver cirrhosis. However, the effect of corticosteroid replacement on mortality …

Introduction Data are sparse as to whether obesity influences the risk of death in critically ill
patients with septic shock. We sought to examine the possible impact of obesity, as assessed …

Background: The objective of this study was to determine whether caloric intake independently
influences mortality and morbidity of critically ill patients. Methods: The study was …

Objectives: To examine the predisposing factors for hypoglycemia in medical-surgical intensive
care unit patients treated with intensive insulin therapy and to assess its association with …

Introduction The clinical significance of elevation of lactate levels within the reference range
is not well studied. The objective of this study was to determine the best cutoff threshold for …

Background The guidelines for initial empiric antimicrobial therapy for ventilator-associated
pneumonia (VAP) are highly dependent on the type of causative pathogen and the time of …

BACKGROUND: Ventilator-associated pneumonia (VAP) prevention is an important patient
safety initiative. We describe the impact of a multidisciplinary surveillance program on VAP …

Hospital mortality rates are elevated in critically ill patients with bloodstream infections.
Given that mortality may be even higher if appropriate treatment is delayed, we sought to …

Background Shorter-duration antibiotic treatment is sufficient for a range of bacterial infections,
but has not been adequately studied for bloodstream infections. Our systematic review, …