Frailty, as measured by the modified frailty index-5 (mFI-5), and older age are associated
with increased mortality in the setting of spinal cord injury (SCI). However, there is limited …

Background Subsequent to a diagnosis of a brain tumor, psychological distress has been
associated with negative effects on mental health as well as suicidality. The magnitude of such …

Background Prognostic factors in adolescent and young adult (AYA) glioma are not well
understood. Though clinical and molecular differences between pediatric and adult glioma have …

Purpose To develop an automated triage tool to predict neurosurgical intervention for patients
with traumatic brain injury (TBI). Materials and Methods A provincial trauma registry was …

Dystonic storm or status dystonicus is a life-threatening hyperkinetic movement disorder
with biochemical alterations due to the excessive muscle contractions. The medical …

Clioquinol (CQ) is an FDA-approved topical antifungal agent known to kill cancer cells. This
facilitated the initiation of clinical trials in patients with refractory hematologic malignancies. …

Background: Differences in physician income by gender have been described in numerous
jurisdictions, but few studies have looked at a Canadian cohort with adjustment for …

Importance The decision to withdraw life-sustaining treatment for pediatric patients with severe
traumatic brain injury (TBI) is challenging for clinicians and families with limited evidence …

Purpose Acute respiratory distress syndrome (ARDS) is common in patients with acute
brain injury admitted to the ICU. We aimed to identify factors associated with ARDS in this …

BACKGROUND There is conflicting evidence regarding the relationship between trauma
center type and mortality for children with traumatic brain injuries. Identification of mortality …