Purpose An increasing proportion of patients (> 30%) with node-positive breast cancer will
obtain an axillary pathologic complete response after neoadjuvant chemotherapy (NAC). If …

The kinase inhibitor p27 Kip1 regulates the G 1 cell cycle phase. Here, we present data
indicating that the oncogenic kinase Src regulates p27 stability through phosphorylation of p27 …

Estrogen drives both transcriptional activation and proteolysis of estrogen receptor α (ERα;
encoded by ESR1). Here we observed variable and overlapping ESR1 mRNA levels in 200 …

Despite growing interest in using large language models (LLMs) in healthcare, current
explorations do not assess the real-world utility and safety of LLMs in clinical settings. Our …

Triple‐negative breast cancer ( TNBC ), the most refractory subtype of breast cancer to current
treatments, accounts disproportionately for the majority of breast cancer‐related deaths. …

Purpose Chloroquine has demonstrated anti-tumor activities through autophagy inhibition
and cell cycle disruption. This study aimed to assess the effect of single-agent chloroquine on …

Background This study aimed to compare the cost and resource use between our first-year
experience using breast-conserving surgery (BCS) with radioactive seed localization (RSL) …

PURPOSE Patients with locally advanced breast cancer (LABC) typically undergo staging
tests at presentation. If staging does not detect metastases, treatment consists of curative …

Importance Contrary to practice guidelines, breast magnetic resonance imaging (MRI) is
commonly used in the preoperative evaluation of women with breast cancer. While existing …

Triple-negative breast cancer (TNBC) is the most refractory subtype of breast cancer. It causes
the majority of breast cancer-related deaths, which has been largely associated with the …