Background For 3–4% of pregnancies, the fetus will be in the breech presentation at term.
For most of these women, the approach to delivery is controversial. We did a randomised trial …

Background The outcome of childhood asthma in adults has been described in high-risk
cohorts, but few population-based studies have reported the risk factors for persistence and …

Background Breastfeeding is widely advocated to reduce risk of atopy and asthma, but the
evidence for such an effect is conflicting. We aimed to assess long-term outcomes of asthma …

Background: Cancer Care Ontario's Systemic Therapy Task Force recently reviewed the
medical oncology system in the province. There has been growing concern about anecdotal …

Economic evaluation is often seen as a branch of health economics divorced from mainstream
econometric techniques. Instead, it is perceived as relying on statistical methods for …

Background As the interval between rupture of the fetal membranes at term and delivery
increases, so may the risk of fetal and maternal infection. It is not known whether inducing labor …

Objective: To define the strengths and weaknesses of existing research on the natural history
of cervical squamous intraepithelial lesions (SIL) and to estimate rates of progression and …

Background Twin birth is associated with a higher risk of adverse perinatal outcomes than
singleton birth. It is unclear whether planned cesarean section results in a lower risk of …

Objective To estimate the likelihood of live birth and the impact of prognostic factors among
untreated infertile couples. Design Cohort follow-up study. Setting Eleven infertility clinics in …

Background One course of antenatal corticosteroids reduces the risk of respiratory distress
syndrome and neonatal death. Weekly doses given to women who remain undelivered after …