Background Streptococcus pneumoniae is a common cause of community acquired pneumonia
and bacteremia. Excess wintertime mortality related to pneumonia has been noted for …

Campylobacter species infections are a common cause of acute gastroenteritis, and may
uncommonly be complicated by renal, neurological, and rheumatologic sequelae. Although …

Invasive meningococcal disease (IMD) is an important cause of meningitis and bacteremia
worldwide. Seasonal variation in IMD incidence has long been recognized, but mechanisms …

Melioidosis, which is infection with the gram-negative bacterium Burkholderia pseudomallei,
is an important cause of sepsis in east Asia and northern Australia. In northeastern Thailand…

The emergence of virulent Plasmodium falciparumin Africa within the past 6000 years as a
result of a cascade of changes in human behavior and mosquito transmission has recently …

Delivering therapeutics deep into damaged tissue during bleeding is challenging because
of the outward flow of blood. When coagulants cannot reach and clot blood at its source, …

A major obstacle to malaria elimination is the great capacity of the parasite and vector
populations to evolve in response to malaria control interventions. The widespread use of …

Background We aimed to assess efficacy and safety, with a special focus on cardiovascular
safety, of the novel dual GIP and GLP-1 receptor agonist tirzepatide versus insulin glargine …

… Arterial thromboses are typically described as white clots reflecting their predominant
platelet-rich composition, whereas venous clots typically appear red due to red blood cells …

The development of a portfolio of COVID-19 vaccines to vaccinate the global population
remains an urgent public health imperative 1 . Here we demonstrate the capacity of a subunit …