Objectives The association between breastfeeding and child cognitive development is
conflicted by studies reporting positive and null effects. This relationship may be confounded by …

Inflammation plays a critical role in host defense, maintaining cellular and tissue integrity
following chemical, physical and biological insults. Inflammation presents in a variety of acute …

Background Physicians face competing demands of maximizing pathogen coverage while
minimizing unnecessary use of broad-spectrum antibiotics when managing sepsis. We …

Background Several efflux and uptake transporters in the placenta are involved in the
transmembrane transport of endogenous substrates and xenobiotics. Their expression and …

Drug efflux transporters in the placenta can significantly influence the materno-fetal transfer
of a diverse array of drugs and other xenobiotics. To determine if clinically important drug …

Background Among patients taking warfarin, lower socioeconomic status is associated with
poorer control of anticoagulation. However, the extent to which socioeconomic status …

… Author links open overlay panel Alex M. Cressman MSc 1 2 , Aniket Natekar MSc 1 ,
Eunji Kim MHSc 1 , Gideon Koren MD FRCPC, FACMT 1 2 , Pina Bozzo HBSc 1 …

Background/context Unnecessary laboratory testing leads to considerable healthcare costs.
Aspartate aminotransferase (AST), commonly ordered with alanine aminotransferase (ALT) …

Question Despite being highly motivated to quit, many of my patients struggle with smoking
cessation during pregnancy. Can you comment on the current treatment options and discuss …

Demand for Personal Protective Equipment (PPE) such as surgical masks, gloves, and gowns
has increased significantly since the onset of the COVID-19 pandemic. In hospital settings…