Objective The aim of this study was to provide an overview of the recommendations regarding
the diagnosis and treatment contained in current clinical practice guidelines for patients …

The targeted and efficiency-oriented delivery of (therapeutic) nucleic acids raises hope for
successful gene therapy, ie, for the local and individual treatment of acquired and inherited …

Importance Reassurance is a core aspect of daily medical practice, yet little is known on
how it can be achieved. Objective To determine whether patient education in primary care …

Low back pain is the leading cause of years lived with disability globally. In 2018, an
international working group called on the World Health Organization to increase attention on the …

Disability is an important outcome from a clinical and public health perspective. However, it
is unclear how disability develops in people with low back pain or neck pain. More …

Asymmetric flow field-flow fractionation (AF4) is a widely used and versatile technique in the
family of field-flow fractionations, indicated by a rapidly increasing number of publications. It …

• Most low-back pain with or without radicular pain or neurogenic claudication does not
require immediate diagnostic imaging and can be managed in primary care.• All patients with …

Benchmarking is critical when evaluating performance, but is especially difficult for file and
storage systems. Complex interactions between I/O devices, caches, kernel daemons, and …

Eyetracking is commonly used to investigate attentional bias. Although some studies have
investigated the internal consistency of eyetracking, data are scarce on the test–retest …

Evidence from randomized controlled studies shows that reconceptualizing pain improves
patients’ knowledge of pain biology, reduces catastrophizing thoughts, and improves pain …