Objective The purpose of this paper is to summarize the best evidence regarding the impact
of providing patient-reported outcomes (PRO) information to health care professionals in …

Background Heart failure (HF) is an increasingly common condition affecting patients’ health-related
quality of life (HRQL). However, there is little literature comparing HF-specific …

Background Patient‐reported outcomes measures (PROMs) assess a patient’s subjective
appraisal of health outcomes from their own perspective. Despite hypothesised benefits that …

Quality-of-life (QOL) instruments used in clinical research can provide important evidence to
inform decisions about alternative treatments. This is particularly true when patients, such as …

Background: Clinical guidelines should be updated to maintain their validity. Our aim was to
estimate the length of time before recommendations become outdated. Methods: We used a …

Background: The mass availability and use of mobile health (mHealth) technologies offers
the potential for these technologies to support or substitute medical advice. However, it is …

Spinal muscular atrophy (SMA) is a rare, progressive neuromuscular disease characterized
by loss of motor neurons and muscle atrophy. Untreated infants with type 1 SMA do not …

Background Clinical guidelines (CGs) are popular for healthcare decision making but their
acceptability and use by healthcare providers is influenced by numerous factors. Some of …

Aims Schizophrenia has the highest median societal cost per patient of all mental disorders.
This review summarizes the different costs/cost drivers (cost components) associated with …

Background A major challenge in updating clinical guidelines is to efficiently identify new,
relevant evidence. We evaluated the efficiency and feasibility of two new approaches: the …