Glutamate excitotoxicity plays an important role in the development of secondary injuries that
occur following traumatic brain injury (TBI), and contributes significantly to expansion of the …

Hepatic encephalopathy (HE) is a neuropsychiatric disorder that occurs in both acute and
chronic liver failure. Although the precise pathophysiologic mechanisms responsible for HE …

Cerebral damage as a consequence of glutamate-mediated excitotoxicity represents a major
consequence of stroke. However, the development of effective clinical treatments for this …

The Long-Wavelength Spectrometer (LWS) is one of two complementary spectrometers aboard
the European Space Agency's Infrared Space Observatory (ISO) (Kessler et al., 1996). It …

The central nervous system, and the basal ganglia in particular, is an important target in
manganese neurotoxicity, a disorder producing neurological symptoms similar to that of …

Thiamine deficiency (TD) is a well-established model of Wernicke's encephalopathy.
Although the neurologic dysfunction and brain damage resulting from the biochemical …

Thiamine is an essential vitamin that is necessary to maintain the functional integrity of cells
in the brain. Its deficiency is the underlying cause of Wernicke’s encephalopathy (WE), a …

Wernicke's Encephalopathy (WE) is a serious neurological disorder resulting from thiamine
deficiency, encountered in chronic alcoholics and in patients with grossly impaired nutritional …

Emerging evidence suggests that thiamine deficiency (TD), the cause of Wernicke's
encephalopathy, produces alterations in brain function and structural damage that closely model a …

A better understanding of how hemodynamic factors affect the integrity and function of the
vascular endothelium is necessary to appreciate more fully how atherosclerosis is initiated …