User profiles for A. Arnaout

Adnan Arnaout

Prevail Therapeutics & City University of New York
Verified email at prevailtherapeutics.com
Cited by 427

Carbon nanotubes in biomedical applications: factors, mechanisms, and remedies of toxicity: miniperspective

R Alshehri, AM Ilyas, A Hasan, A Arnaout… - Journal of medicinal …, 2016 - ACS Publications
Carbon nanotubes (CNTs) represent one of the most studied allotropes of carbon. The unique
physicochemical properties of CNTs make them among prime candidates for numerous …

MRI for detection of extramural vascular invasion in rectal cancer

NJ Smith, O Shihab, A Arnaout… - American Journal of …, 2008 - Am Roentgen Ray Soc
OBJECTIVE. Extramural vascular invasion is a pathologic feature predictive of distant relapse
and poor survival among patients with colorectal cancer. This article illustrates the use of …

Sentinel node biopsy after neoadjuvant chemotherapy in biopsy-proven node-positive breast cancer: the SN FNAC study

…, L Sideris, S Meterissian, A Arnaout… - Journal of Clinical …, 2015 - ascopubs.org
Purpose An increasing proportion of patients (> 30%) with node-positive breast cancer will
obtain an axillary pathologic complete response after neoadjuvant chemotherapy (NAC). If …

Sites of distant recurrence and clinical outcomes in patients with metastatic triple‐negative breast cancer: high incidence of central nervous system metastases

NU Lin, E Claus, J Sohl, AR Razzak, A Arnaout… - Cancer, 2008 - Wiley Online Library
BACKGROUND. The purpose of the current study was to characterize the outcomes of
patients with metastatic triple‐negative breast cancers, including the risk and clinical …

Estrogen, progesterone, and HER2/neu receptor discordance between primary and metastatic breast tumours—a review

…, I Kuchuk, X Zhu, K Gelmon, A Arnaout - Cancer and Metastasis …, 2016 - Springer
Discordance in estrogen (ER), progesterone (PR), and HER2/neu status between primary
breast tumours and metastatic disease is well recognized. In this review, we highlight how …

[HTML][HTML] p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2

I Chu, J Sun, A Arnaout, H Kahn, W Hanna, S Narod… - Cell, 2007 - cell.com
The kinase inhibitor p27 Kip1 regulates the G 1 cell cycle phase. Here, we present data
indicating that the oncogenic kinase Src regulates p27 stability through phosphorylation of p27 …

Vegf-a, vegf-c, and vegf-d in colorectal cancer progression

ML George, MG Tutton, F Janssen, A Arnaout… - Neoplasia, 2001 - Elsevier
We aimed to assess the relationship of the angiogenic cytokines VEGF-A, VEGF-C, and
VEGF-D and their receptors VEGFR-2 and VEGFR-3 in the adenomacarcinoma sequence and …

Clinical outcomes and treatment practice patterns of patients with HER2-positive metastatic breast cancer in the post-trastuzumab era

EM Olson, JS Najita, J Sohl, A Arnaout, HJ Burstein… - The Breast, 2013 - Elsevier
BACKGROUND: Trastuzumab is associated with improvements in overall survival (OS)
among patients with HER2-positive metastatic breast cancer (MBC); however disease course …

Accuracy of multidetector computed tomography in identifying poor prognostic factors in colonic cancer

…, H Blake, MD Koh, I Swift, A Arnaout… - Journal of British …, 2010 - academic.oup.com
Background Recent neoadjuvant strategies for high-risk colonic tumours have renewed
interest in accurate preoperative staging. The aim of this study was to validate prospectively the …

Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

…, L Faivre, C Antzelevitch, S Kääb, AA Arnaout… - Nature …, 2022 - nature.com
Brugada syndrome (BrS) is a cardiac arrhythmia disorder associated with sudden death in
young adults. With the exception of SCN5A, encoding the cardiac sodium channel Na V 1.5, …