Methods A hybrid approach based on established processes described by Glaser15 and by
the National Institutes of Health (http://prevention. nih. gov/cdp/about. aspx) 16 was used to …

Purpose— To critically review and evaluate the science behind individual eligibility criteria (indication/inclusion
and contraindications/exclusion criteria) for intravenous recombinant …

Background Trials examining the benefit of thrombectomy in anterior circulation proximal
large vessel occlusion stroke have enrolled patients considered to have salvageable brain …

… Andrew Demchuk helped with the study, collected data, and cowrote the paper. Jinjin
Zhang helped with the design and carried out the analyses. Alastair Buchan invented the …

Background Among patients with a proximal vessel occlusion in the anterior circulation, 60
to 80% of patients die within 90 days after stroke onset or do not regain functional …

Background In 2015, five randomised trials showed efficacy of endovascular thrombectomy
over standard medical care in patients with acute ischaemic stroke caused by occlusion of …

Background We aimed to assess the safety and efficacy of thrombectomy for the treatment
of stroke in a trial embedded within a population-based stroke reperfusion registry. Methods …

Background Thrombectomy is currently recommended for eligible patients with stroke who
are treated within 6 hours after the onset of symptoms. Methods We conducted a multicenter, …

Background Endovascular therapy is increasingly used after the administration of intravenous
tissue plasminogen activator (t-PA) for patients with moderate-to-severe acute ischemic …

… Dr Demchuk reports receiving grant support and personal fees from Covidien/Medtronic
and personal fees from Pulse Therapeutics. Dr Devlin reports that his institutions received …