The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

BS Park, DH Song, HM Kim, BS Choi, H Lee, JO Lee - Nature, 2009 - nature.com
… Comparison with the recently published structure of the monomeric TLR4 and MD-2
complex shows that the overall folding of TLR4 and MD-2 is not disturbed by LPS binding or …

The ubiquitin-proteasome pathway and pathogenesis of human diseases

AL Schwartz, PhD, MD… - Annual review of …, 1999 - annualreviews.org
The ubiquitin-proteasome pathway plays a pivotal role in the degradation of short-lived and
regulatory proteins important in a variety of basic cellular processes, including regulation of …

Molecular dynamics (MD) simulation of uniaxial tension of some single-crystal cubic metals at nanolevel

R Komanduri, N Chandrasekaran, LM Raff - International Journal of …, 2001 - Elsevier
… An alternative approach is MD simulations. Even though the … , MD simulations of tension
are carried out to study the behavior of a range of single crystal cubic metals, both FCC (Al, Cu, …

MD simulation of indentation and scratching of single crystal aluminum

R Komanduri, N Chandrasekaran, LM Raff - Wear, 2000 - Elsevier
… Molecular Dynamics (MD) simulations of indentation and scratching have been conducted
on single crystal aluminum in various crystal orientations and directions of scratching to …

and MD LOVELESS

JL Hamrick, MJW Godt… - Genetics and conservation …, 1991 - books.google.com
One goal of conservation biology is to preserve the evolutionary potential of species by
maintaining natural levels of genetic diversity. Knowledge of the levels and distribution of genetic …

Insights into direct nose to brain delivery: current status and future perspective

D Mittal, A Ali, S Md, S Baboota, JK Sahni, J Ali - Drug delivery, 2014 - Taylor & Francis
… and the possibility of employing biocompatible and biodegradable materials (Cho et al.,
Citation2008). Md and coworkers formulated BRC-loaded chitosan nanoparticles (CS NPs) by …

Innate recognition of lipopolysaccharide by Toll-like receptor 4–MD-2

K Miyake - Trends in microbiology, 2004 - cell.com
… (TLR) 4–MD-2 complex. CD14 binds and concentrates LPS and presents it to TLR4–MD-2,
which delivers a signal through the plasma membrane. RP105–MD-1 is a structurally related …

[PDF][PDF] Biosurfactant: production and application

F Md - J Pet Environ Biotechnol, 2012 - researchgate.net
… Muthusamy et al. [9] reported that pretreatment of silicone rubber with S. thermophilus …
response was demonstrated when low molecular mass antigens Iturin AL and herbicolin A [22]. …

Bromocriptine loaded chitosan nanoparticles intended for direct nose to brain delivery: pharmacodynamic, pharmacokinetic and scintigraphy study in mice model

S Md, RA Khan, G Mustafa, K Chuttani… - European Journal of …, 2013 - Elsevier
The primary aim of this study was to investigate the potential use of chitosan nanoparticles
as a delivery system to enhance the brain targeting efficiency of bromocriptine (BRC) …

Essential role of MD-2 in LPS responsiveness and TLR4 distribution

Y Nagai, S Akashi, M Nagafuku, M Ogata… - Nature …, 2002 - nature.com
… We also examined TLR4 −/− mice 11 , which did not express TLR4–MD-2 due to the absence
of TLR4 and showed MD-2 mRNA expression was not altered in the absence of TLR4 (Fig. …