While there is consensus on starting urate-lowering therapy (ULT) in cases of symptomatic
hyperuricemia, the frequent condition of asymptomatic hyperuricemia (AH) remains a …

Background. The incidence of gout has been rapidly increasing in recent years with the
changing of diet. At present, modern medications used in the clinical treatment of gout …

Objective To evaluate the risk of severe infection and infection-related mortality among
patients with newly diagnosed SLE. Methods We conducted an age-and gender-matched …

Background The use of tramadol among osteoarthritis (OA) patients has been increasing
rapidly around the world, but population-based studies on its safety profile among OA …

Rationale & Objective Allopurinol should be started at lower doses in patients with chronic
kidney disease (CKD) to avoid adverse effects. We examined the risk of severe cutaneous …

Objective This study aimed to evaluate the effect of traditional Chinese medicine (TCM) on
endpoint events in patients with gouty arthritis (GA). Methods and Materials A total of 2091 …

Allopurinol hypersensitivity syndrome includes Stevens–Johnson syndrome, toxic epidermal
necrolysis and drug reaction with eosinophilia and systemic symptoms. It affects about 1 in …

The article discusses modern approaches to the gout treatment, presented in foreign and
domestic clinical guidelines. While the use of urate-lowering therapy for gout is a necessary …

Females present a higher risk of adverse drug reactions. Sex‐related differences in drug
concentrations may contribute to these observations but they remain understudied given the …

Результаты терапии подагры у многих пациентов остаются неудовлетворительными,
несмотря на доступность лекарственных средств и наличие рекомендаций по ее …