Background: Previous studies have reported rapid increases in anal cancer incidence rates
in seven high-income countries in North America, Europe and Oceania. There is very limited …

Anal intraepithelial neoplasia (AIN) is a premalignant lesion for anal cancer. It is more
commonly found in high-risk patients (eg, human papilloma virus (HPV)/human …

Although there are no consensus screening guidelines for anal cancer, it is reasonable to
screen high-risk populations with physical examination, anal cytology and HRA …

Background There is no consensus on screening strategy of high-grade intraepithelial
neoplasia (HGAIN). Guidelines range from clinical examination with digital anorectal …

Introduction Current smoking is a risk factor for anal cancer. Yet, its association with anal
human papillomavirus infection (HPV) and anal high-grade squamous intraepithelial lesions …

Human papillomavirus (HPV) infection is the cause of anal squamous cell cancer (ASCC) in
80% of cases. Available research has also shown high prevalence of anal HPV infection …

Objective The aim of the study was to evaluate the validity of anal cytology against high-
resolution anoscopy in the detection of anal high-grade squamous intraepithelial lesions …

Background Socioeconomic status (SES) is associated with diagnostic and treatment delays
and survival in multiple cancers, but less data exist for anal squamous cell carcinoma …

Introduction Anal squamous cell carcinoma (ASCC) is relatively rare, but its incidence and
mortality have been steadily climbing in marginalized populations. We explored the impact …

Background Human papilloma virus infection is responsible for approximately 31,500 new
cancers in the United States annually. Almost all cervical cancers are linked to human …