Psychedelics have inspired new hope for treating brain disorders, as they seem to be unlike
any treatments currently available. Not only do they produce sustained therapeutic effects …

This review assesses the abuse potential of medically-administered psilocybin, following the
structure of the 8 factors of the US Controlled Substances Act (CSA). Research suggests the …

Background: Meta-analysis of randomized studies using lysergic acid diethylamide (LSD) for
alcohol use disorder (AUD) showed large, significant effects for LSD efficacy compared to …

Rationale Is it possible to have a psychedelic experience from a placebo alone? Most
psychedelic studies find few effects in the placebo control group, yet these effects may have …

How do psychedelic drugs produce their characteristic range of acute effects in perception,
emotion, cognition, and sense of self? How do these effects relate to the clinical efficacy of …

Unipolar mood disorders, including major depressive disorder and persistent depressive
disorder (dysthymia), confer high rates of disability and mortality and a very high …

Hallucinogens fall into several different classes, as broadly defined by pharmacological
mechanism of action, and chemical structure. These include psychedelics, entactogens …

Psychedelics were used in the treatment of psychiatric conditions prior to their prohibition in
the late 1960s. In the past three decades, there is a revived research interest in the …

Though there was initial interest in the use of psychedelic drugs for psychiatric treatment,
bad outcomes and subsequent passage of the Substance Act of 1970, which placed …

Research since the 1950s has shown that psychedelic-assisted psychotherapy has had
significant positive effects in reductions of specific clinical symptoms and increases in quality …