Background Although there is a strong biological rationale for early decompression of the
injured spinal cord, the influence of the timing of surgical decompression for acute spinal …

Traumatic brain injury (TBI) and spinal cord injury (SCI) are devastating conditions with far-
reaching physical, emotional, and economic consequences for patients, families, and …

Orthostatic challenge produced by upright posture may lead to syncope if the cardiovascular
system is unable to maintain adequate brain perfusion. This review outlines orthostatic …

Spinal cord injury is a disabling disorder, worldwide spread, with important consequences
on functioning and health conditions and impacts on physical, psychological, and social well …

Objective To assess the discriminative ability of the Risk Analysis Index-administrative (RAI-
A) and its recalibrated version (RAI-Rev), compared to the 5-factor modified frailty index (mFI …

Although experience suggests a shift in the epidemiology of spinal cord injury (SCI) toward
an older demographic, population studies are lacking. We aimed to evaluate (1) how the …

As the incidence of traumatic spinal cord injury (tSCI) in the elderly rises, clinicians are
increasingly faced with difficult discussions regarding aggressiveness of management …

Frailty negatively affects outcome in elective spine surgery populations. This study sought to
determine the effect of frailty on patient outcome after traumatic spinal cord injury (tSCI) …

Objective The aim of this study was to determine if baseline frailty was an independent
predictor of adverse events (AEs) and in-hospital mortality in patients being treated for acute …

Dementia primarily affects an individual's cognitive func tion and many aspects of life are
negatively affected by cognitive decline. There are no approved disease-modifying drugs …