The most common bacterial cause of pharyngitis is infection by Group A β-hemolytic
streptococcus (GABHS), commonly known as strep throat. 5–15% of adults and 15–35% of …

Background Group A streptococcus (GAS) accounts for 20% to 40% of cases of pharyngitis
in children; the remaining cases are caused by viruses. Compared with throat culture, rapid …

Most randomized controlled trials evaluating medical interventions have a pre-specified
hypothesis, which is statistically tested against the null hypothesis of no effect. In diagnostic …

Objective To provide family physicians with an updated approach to diagnosis and treatment
of pharyngitis, detailing key symptoms, methods of investigation, and a summary of common …

Nearly a century after rheumatic fever (RF) and rheumatic heart disease (RHD) was
eradicated from the developed world, the disease remains endemic in many low-and middle …

Background Acute pharyngitis is one of the most common conditions in outpatient settings
and an important source of inappropriate antibiotic prescribing. Rapid antigen detection …

Background Sore throat is a common condition caused by viruses or bacteria, and is a
leading cause of antibiotic prescription in primary care. The most common bacterial species …

Background To compare the sensitivity and specificity of the recommended 2-step rapid
antigen detection test (RADT) with confirmatory culture vs the point-of-care (POC) …

Objectives To assess recent community antibiotic prescribing for French children and
identify areas of potential improvement. Methods We analysed 221 768 paediatric (< 15 …

Background Acute rheumatic fever (ARF) has largely disappeared from high-income
countries. However, in New Zealand (NZ) rates remain high in indigenous (Māori) and …