Background There is a growing number of trials examining the effectiveness of
pharmacotherapies for obesity, however, little is known about placebo and nocebo effect in …

Participation in randomised clinical trials (RCTs) entails taking part in the discovery of effects
of health care interventions. The question of whether participants' outcomes are different to …

Background Previous reviews examining the effect of participation in trials on outcomes
have not consistently shown benefit. Obstetrics and gynaecology is a unique disease area …

Importance Many cancer clinical investigators view clinical trials as offering better care for
patients than routine clinical care. However, definitive evidence of clinical benefit from trial …

Institutional review boards, which are charged with overseeing research, must classify the
riskiness of proposed research according to a federal regulation known as the Common …

Mounting evidence suggests that participation in clinical trials confers neither advantage nor
disadvantage on those enrolled. Narrow focus on the question of a “trial effect,” however …

Randomized clinical trials (RCTs) of lifestyle modification have reported beneficial effects of
interventions, compared to control. Whether participation in the control group has benefits is …

Background: Recruitment and retention of participants in clinical trials for Parkinson's
disease (PD) is challenging. A qualitative study embedded in the PD STAT multi-centre …

Abstract Knowledge translation (KT) involves implementation of evidence-based strategies
and guidelines into practice to improve the process of care and health outcomes for patients …

Randomized clinical trials (RCTs) of lifestyle modification have reported beneficial effects of
interventions, compared to control. Whether participation in the control group has benefits is …