Targeting chemokines and chemokine receptors in multiple sclerosis and experimental autoimmune encephalomyelitis

S Dhaiban, M Al-Ani, NM Elemam… - Journal of …, 2020 - Taylor & Francis
Multiple sclerosis (MS) is an immune-mediated and neurodegenerative disorder that results
in inflammation and demyelination of the central nervous system (CNS). MS symptoms …

Neural stem cell-based regenerative approaches for the treatment of multiple sclerosis

J Xiao, R Yang, S Biswas, Y Zhu, X Qin, M Zhang… - Molecular …, 2018 - Springer
Multiple sclerosis (MS) is a chronic, autoimmune, inflammatory, and demyelinating disorder
of the central nervous system (CNS), which ultimately leads to axonal loss and permanent …

Designing drug-free biodegradable nanoparticles to modulate inflammatory monocytes and neutrophils for ameliorating inflammation

E Saito, R Kuo, RM Pearson, N Gohel… - Journal of controlled …, 2019 - Elsevier
Inflammation associated with autoimmune diseases and chronic injury is an initiating event
that leads to tissue degeneration and dysfunction. Inflammatory monocytes and neutrophils …

dNP2 is a blood–brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis

S Lim, WJ Kim, YH Kim, S Lee, JH Koo, JA Lee… - Nature …, 2015 - nature.com
Central nervous system (CNS)-infiltrating effector T cells play critical roles in the
development and progression of multiple sclerosis (MS). However, current drugs for MS are …

Effect of applying inclusion and exclusion criteria of phase III clinical trials to multiple sclerosis patients in routine clinical care

KO Jalusic, D Ellenberger, P Rommer… - Multiple Sclerosis …, 2021 - journals.sagepub.com
Background: Newly approved, drug-modifying therapies are associated with still unknown
adverse events, although clinical trials leading to approval have strict inclusion and …

Thyroid hormone potentially benefits multiple sclerosis via facilitating remyelination

M Zhang, Z Ma, H Qin, Z Yao - Molecular neurobiology, 2016 - Springer
Myelin destruction due to inflammatory damage of oligodendrocytes (OLs) in conjunction
with axonal degeneration is one of the major histopathological hallmarks of multiple …

[HTML][HTML] An eight-week randomised controlled trial of home-based pilates for symptoms of anxiety, depression, and fatigue among people with MS with minimal-to-mild …

KM Fleming, SB Coote, MP Herring - Mental Health and Physical Activity, 2020 - Elsevier
Background Evidence supports positive effects of exercise on mental health outcomes
among people with Multiple Sclerosis (PwMS). However, non-traditional exercise modes like …

Factors interfering with parenthood decision-making in an Italian sample of people with multiple sclerosis: an exploratory online survey

L Lavorgna, S Esposito, R Lanzillo, M Sparaco… - Journal of …, 2019 - Springer
Background Little is known about the influence of multiple sclerosis (MS) diagnosis on
parenthood attitude in people with MS (pwMS). Objective To investigate the impact of …

Trifluoperazine reduces cuprizone-induced demyelination via targeting Nrf2 and IKB in mice

E Khaledi, T Noori, A Mohammadi-Farani… - European journal of …, 2021 - Elsevier
Multiple sclerosis (MS) is one of the most common neurodegenerative diseases. In this
disease, the immune system attacks oligodendrocyte cells and the myelin sheath of …

Exploring Multiple Sclerosis (MS) and Amyotrophic Lateral Scler osis (ALS) as neurodegenerative diseases and their treatments: a review study

O Deeb, M Nabulsi - Current Topics in Medicinal Chemistry, 2020 - ingentaconnect.com
Growing concern about neurodegenerative diseases is becoming a global issue. It is
estimated that not only will their prevalence increase but also morbidity and health burden …