Prophylaxis of Mycobacterium tuberculosis H37Rv infection in a preclinical mouse model via inhalation of nebulized bacteriophage D29

NB Carrigy, SE Larsen, V Reese, T Pecor… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Globally, more people die annually from tuberculosis than from any other single infectious
agent. Unfortunately, there is no commercially available vaccine that is sufficiently effective …

Vitamin D, serum 25 (OH) D, LL-37 and polymorphisms in a Canadian First Nation population with endemic tuberculosis

L Larcombe, N Mookherjee, J Slater… - … journal of circumpolar …, 2015 - Taylor & Francis
Background Canadian First Nation populations have experienced endemic and epidemic
tuberculosis (TB) for decades. Vitamin D–mediated induction of the host defence peptide LL …

[HTML][HTML] Can we eliminate tuberculosis?: Addressing tuberculosis among Inuit in Canada

M Patterson, S Flinn, K Barker - Canada Communicable Disease …, 2018 - ncbi.nlm.nih.gov
The average annual rate of tuberculosis (TB) among Inuit in Canada is now more than 290
times higher than Canadian born non-Indigenous people. How did this happen? Using the …

Inadequate Diet Is Associated with Acquiring Mycobacterium tuberculosis Infection in an Inuit Community. A Case–Control Study

GJ Fox, RS Lee, M Lucas, FA Khan… - Annals of the …, 2015 - atsjournals.org
Background: Tuberculosis predominantly affects socioeconomically disadvantaged
communities. The extent to which specific dietary and lifestyle factors contribute to …

The eight ujarait (rocks) model: Supporting Inuit adolescent mental health with an intervention model based on Inuit ways of knowing

GK Healey, J Noah, C Mearns - International Journal of …, 2016 - jps.library.utoronto.ca
Objective: This study responded to a community-identified need to form an evidence base
for interventions to promote mental health and wellness among youth in Nunavut. Methods …

[HTML][HTML] Evaluation of TB elimination strategies in Canadian Inuit populations: Nunavut as a case study

E Abdollahi, Y Keynan, P Foucault, J Brophy… - Infectious Disease …, 2022 - Elsevier
Tuberculosis (TB) continues to disproportionately affect Inuit populations in Canada with
some communities having over 300 times higher rate of active TB than Canadian-born, non …

[HTML][HTML] Stochastic agent-based modeling of tuberculosis in Canadian Indigenous communities

AR Tuite, V Gallant, E Randell, AC Bourgeois… - BMC public health, 2017 - Springer
Abstract Background In Canada, active tuberculosis (TB) disease rates remain
disproportionately higher among the Indigenous population, especially among the Inuit in …

[HTML][HTML] Application of whole genome sequence analysis to the study of Mycobacterium tuberculosis in Nunavut, Canada

AD Tyler, E Randell, M Baikie, K Antonation… - PLoS …, 2017 - journals.plos.org
Canada has one of the lowest rates of tuberculosis (TB) in the world, however, among
certain sub-populations, disease incidence rates approach those observed in sub-Saharan …

A cross-sectional study exploring community perspectives on the impacts of COVID-19 in Nunavut and recommendations for a Holistic Inuit Qaujimajatuqangit …

Z Rana, M Leach, GK Healey Akearok… - … of Circumpolar Health, 2024 - Taylor & Francis
The goal of this study was to examine and address critical knowledge gaps and develop an
understanding of both the positive and negative societal outcomes resulting from the public …

[HTML][HTML] SARS-CoV-2 surveillance system in Canada: longitudinal trend analysis

L Post, MJ Boctor, TZ Issa, CB Moss… - JMIR Public Health …, 2021 - publichealth.jmir.org
Background: The COVID-19 global pandemic has disrupted structures and communities
across the globe. Numerous regions of the world have had varying responses in their …