Background Breathlessness is a common and disabling symptom which affects many
people with advanced cardiorespiratory disease and cancer. The most effective treatments …

Pain is a frequent and significant problem for children with impairment of the central nervous
system, with the highest frequency and severity occurring in children with the greatest …

Rationale Advanced fibrosing interstitial lung disease (ILD) is often progressive and
associated with a high burden of symptoms and poor prognosis. Little is known about the …

Background and objective The management of symptoms in patients with advanced chronic
respiratory diseases needs more attention. This review summarizes the latest evidence on …

Previous studies have shown that opioids can reduce chronic breathlessness in advanced
disease. However, physicians remain reluctant to prescribe opioids for these patients …

Chronic breathlessness is a major cause of suffering in chronic obstructive pulmonary
disease (COPD)[1]. Despite the impact on patients' daily lives, chronic breathlessness might …

Classically, hospice and palliative services have been most available to and
disproportionately used by patients with cancer. No data exist on community outpatient …

Background Chronic breathlessness is a recognized clinical syndrome that severely impacts
patients and carers, who become increasingly restricted in their daily activities. Often …

Rationale: A growing evidence base supports provision of palliative care services alongside
life-prolonging care. Whereas palliative care processes have been implemented widely in …

Background Chronic obstructive pulmonary disease (COPD) is a chronic, irreversible
disease and a leading cause of worldwide morbidity and mortality. In Canada, COPD is the …