Abstract The Canadian Cardiovascular Society Guidelines Committee and key Canadian
opinion leaders believed there was a need for up to date guidelines that used the Grading of …

Executive summary Acute kidney injury (AKI) is a major contributor to poor patient outcomes.
AKI occurs in about 13· 3 million people per year, 85% of whom live in the developing world …

Acute kidney injury (AKI) is a widespread problem of epidemic status. Compelling evidence
indicates that the incidence of AKI is rapidly increasing, particularly among hospitalized …

Each year, cardiac complications occur within 30 days after major noncardiac surgery in
more than 10 million people worldwide; postoperative mortality is 1.5%. Enhanced patient …

Perioperative organ injury is among the leading causes of morbidity and mortality of surgical
patients. Among different types of perioperative organ injury, acute kidney injury occurs …

Importance Major adverse cardiovascular and cerebrovascular events (MACCE) are a
significant source of perioperative morbidity and mortality following noncardiac surgery …

BACKGROUND: Among adults undergoing contemporary noncardiac surgery, little is known
about the frequency and timing of death and the associations between perioperative …

Background Few trials of acute kidney injury (AKI) prevention after surgery have been
conducted, and most observational studies focus on AKI following cardiac surgery. The …

Acute kidney injury (AKI), previously termed acute renal failure, is associated with increased
mortality, prolonged hospital stay, and accelerated chronic kidney disease (CKD). Over the …

Importance Statins affect several mechanisms underlying acute kidney injury (AKI).
Objective To test the hypothesis that short-term high-dose perioperative atorvastatin would …