Ascorbic acid: chemistry, biology and the treatment of cancer
J Du, JJ Cullen, GR Buettner - … et Biophysica Acta (BBA)-Reviews on …, 2012 - Elsevier
Since the discovery of vitamin C, the number of its known biological functions is continually
expanding. Both the names ascorbic acid and vitamin C reflect its antiscorbutic properties …
expanding. Both the names ascorbic acid and vitamin C reflect its antiscorbutic properties …
[HTML][HTML] High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer
F Böttger, A Vallés-Martí, L Cahn… - Journal of experimental & …, 2021 - Springer
Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer
agent when administered intravenously and in high doses (high-dose IVC). Early phase …
agent when administered intravenously and in high doses (high-dose IVC). Early phase …
Vitamin C in disease prevention and cure: an overview
The recognition of vitamin C is associated with a history of an unrelenting search for the
cause of the ancient haemorrhagic disease scurvy. Isolated in 1928, vitamin C is essential …
cause of the ancient haemorrhagic disease scurvy. Isolated in 1928, vitamin C is essential …
Intravenous vitamin C for reduction of cytokines storm in acute respiratory distress syndrome
The recent outbreak of Covid19 has required urgent treatments for numerous patients. No
suitable vaccines or antivirals are available for Covid19. The efficiency against Covid19 of …
suitable vaccines or antivirals are available for Covid19. The efficiency against Covid19 of …
Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice
Ascorbic acid is an essential nutrient commonly regarded as an antioxidant. In this study, we
showed that ascorbate at pharmacologic concentrations was a prooxidant, generating …
showed that ascorbate at pharmacologic concentrations was a prooxidant, generating …
High-dose parenteral ascorbate enhanced chemosensitivity of ovarian cancer and reduced toxicity of chemotherapy
Y Ma, J Chapman, M Levine, K Polireddy… - Science translational …, 2014 - science.org
Ascorbate (vitamin C) was an early, unorthodox therapy for cancer, with an outstanding
safety profile and anecdotal clinical benefit. Because oral ascorbate was ineffective in two …
safety profile and anecdotal clinical benefit. Because oral ascorbate was ineffective in two …
Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo
Ascorbate (ascorbic acid, vitamin C), in pharmacologic concentrations easily achieved in
humans by iv administration, selectively kills some cancer cells but not normal cells. We …
humans by iv administration, selectively kills some cancer cells but not normal cells. We …
Dual role of hydrogen peroxide in cancer: possible relevance to cancer chemoprevention and therapy
M López-Lázaro - Cancer letters, 2007 - Elsevier
Accumulating evidence suggests that hydrogen peroxide (H2O2) plays an important role in
cancer development. Experimental data have shown that cancer cells produce high …
cancer development. Experimental data have shown that cancer cells produce high …
[BOOK][B] OZONE.
V Bocci - 2011 - Springer
Is there any reason to write a third book on the topic of oxygen-ozone therapy? The first was
written four years ago for italian physicians, who, for some time, had complained about the …
written four years ago for italian physicians, who, for some time, had complained about the …
[HTML][HTML] Redox interactions of vitamin C and iron: Inhibition of the pro-oxidant activity by deferiprone
VA Timoshnikov, TV Kobzeva, NE Polyakov… - International journal of …, 2020 - mdpi.com
Ascorbic acid (AscH2) is one of the most important vitamins found in the human diet, with
many biological functions including antioxidant, chelating, and coenzyme activities. Ascorbic …
many biological functions including antioxidant, chelating, and coenzyme activities. Ascorbic …