Regulation of endogenic metabolites by rosuvastatin in hyperlipidemia patients: An integration of metabolomics and lipidomics

H Lee, JM Choi, JY Cho, TE Kim, HJ Lee… - Chemistry and physics of …, 2018 - Elsevier
Rosuvastatin is a statin used to treat metabolic syndrome conditions, such as
hyperlipidemia. It is relatively safe; however, fatal rhabdomyolysis or skeletal myopathy can …

Pulmonary targeting potential of rosuvastatin loaded nanostructured lipid carrier: Optimization by factorial design

A Patil-Gadhe, V Pokharkar - International Journal of Pharmaceutics, 2016 - Elsevier
Abstract Rosuvastatin (RSVS), an anti-lipidemic agent suggested for the treatment of airway
remodeling in chronic obstructive pulmonary disease (COPD). It shows a pleiotropic effect …

The use of ezetimibe in achieving low density lipoprotein lowering goals in clinical practice: position statement of a United Kingdom consensus panel

DP Mikhailidis, AS Wierzbicki… - … medical research and …, 2005 - Taylor & Francis
There is no doubt that lowering serum cholesterol levels reduces the risk of major coronary
events. This evidence has led treatment guidelines to set progressively lower targets for low …

A simple assay for the simultaneous determination of rosuvastatin acid, rosuvastatin-5S-lactone, and N-desmethyl rosuvastatin in human plasma using liquid …

JS Macwan, IA Ionita, F Akhlaghi - Analytical and bioanalytical chemistry, 2012 - Springer
A simple and sensitive assay was developed and validated for the simultaneous
quantification of rosuvastatin acid (RST), rosuvastatin-5 S-lactone (RST-LAC), and N …

[HTML][HTML] Serum predose metabolic profiling for prediction of rosuvastatin pharmacokinetic parameters in healthy volunteers

AMR Silveira, GHB Duarte, AMAP Fernandes… - Frontiers in …, 2021 - frontiersin.org
Rosuvastatin is a well-known lipid-lowering agent generally used for hypercholesterolemia
treatment and coronary artery disease prevention. There is a substantial inter-individual …

[HTML][HTML] Risk of rhabdomyolysis with donepezil compared with rivastigmine or galantamine: a population-based cohort study

JL Fleet, E McArthur, A Patel, MA Weir… - CMAJ, 2019 - Can Med Assoc
BACKGROUND: Donepezil, rivastigmine and galantamine are popular cholinesterase
inhibitors used to manage the symptoms of Alzheimer disease and other dementias; …

Rhabdomyolysis-induced compartment syndrome secondary to atorvastatin and strenuous exercise

L Dunphy, R Morhij, S Tucker - Case Reports, 2017 - casereports.bmj.com
A 50-year-old male UK resident with a history of hypertension and hypercholesterolaemia
presented to the emergency department with a 48-hour history of sudden onset bilateral …

Rosuvastatin induced rhabdomyolysis in a low risk patient: a case report and review of the literature

FY Khan, W Ibrahim - Current Clinical Pharmacology, 2009 - ingentaconnect.com
We report a case of rosuvastatin induced rhabdomyolysis in a low risk patient, who
presented with five-day history of generalized muscle pain, weakness and easy fatigability …

Rosuvastatin for the treatment of hypercholesterolemia

NS Culhane, SL Lettieri, JR Skae - … : The Journal of Human …, 2005 - Wiley Online Library
Rosuvastatin, a new hydrophilic 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase
inhibitor (statin), is approved as an adjunct to diet in patients with primary …

Simvastatin-induced rhabdomyolysis and acute renal injury

A Waness, S Bahlas, S Al Shohaib - Blood purification, 2008 - karger.com
Simvastatin is one of the most commonly prescribed CoA reductase inhibitors. The safety
profile of this drug has been widely discussed in the medical and consumer advocacy …