From oxiranes to oligomers: Architectures of US FDA approved pharmaceuticals containing oxygen heterocycles

MD Delost, DT Smith, BJ Anderson… - Journal of Medicinal …, 2018 - ACS Publications
Oxygen heterocycles are the second most common type of heterocycles that appear as
structural components of US Food and Drug Administration (FDA) approved …

H7N9 influenza virus in China

C Li, H Chen - Cold Spring Harbor perspectives …, 2021 - perspectivesinmedicine.cshlp.org
In early 2013, human infections caused by a novel H7N9 avian influenza virus (AIV) were
first reported in China; these infections caused severe disease and death. The virus was …

Modeling the worldwide spread of pandemic influenza: baseline case and containment interventions

V Colizza, A Barrat, M Barthelemy, AJ Valleron… - PLoS …, 2007 - journals.plos.org
Background The highly pathogenic H5N1 avian influenza virus, which is now widespread in
Southeast Asia and which diffused recently in some areas of the Balkans region and …

Orally efficacious broad-spectrum ribonucleoside analog inhibitor of influenza and respiratory syncytial viruses

JJ Yoon, M Toots, S Lee, ME Lee… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Morbidity and mortality resulting from influenza-like disease are a threat, especially for older
adults. To improve case management, next-generation broad-spectrum antiviral …

Inhibition of influenza virus production in virus-infected mice by RNA interference

Q Ge, L Filip, A Bai, T Nguyen… - Proceedings of the …, 2004 - National Acad Sciences
Influenza A virus infection is a major source of morbidity and mortality worldwide. Because
the effectiveness of existing vaccines and antiviral drugs is limited, development of new …

A systematic review of NMDA receptor antagonists for treatment of neuropathic pain in clinical practice

R Aiyer, N Mehta, S Gungor… - The Clinical Journal of Pain, 2018 - journals.lww.com
Objective: To investigate the efficacy of N-methyl-D-aspartate receptor (NMDAR) antagonists
for neuropathic pain (NeuP) and review literature to determine if specific pharmacologic …

Marine algal antioxidants as potential vectors for controlling viral diseases

C Sansone, C Brunet, DM Noonan, A Albini - Antioxidants, 2020 - mdpi.com
As the COVID-19 epidemic expands in the world, and with the previous SARS epidemic,
avian flu, Ebola and AIDS serving as a warning, biomedical and biotechnological research …

Detection of influenza virus: traditional approaches and development of biosensors

Y Amano, Q Cheng - Analytical and bioanalytical chemistry, 2005 - Springer
Influenza is an acute respiratory disease caused by the influenza virus. The disease occurs
annually, causing fatality in the elderly and children and billions of dollars loss in business …

Using Google Trends and ambient temperature to predict seasonal influenza outbreaks

Y Zhang, H Bambrick, K Mengersen, S Tong… - Environment …, 2018 - Elsevier
Background The discovery of the dynamics of seasonal and non-seasonal influenza
outbreaks remains a great challenge. Previous internet-based surveillance studies built …

[HTML][HTML] Potential impact of antiviral drug use during influenza pandemic

R Gani, H Hughes, D Fleming, T Griffin… - Emerging infectious …, 2005 - ncbi.nlm.nih.gov
The recent spread of highly pathogenic strains of avian influenza has highlighted the threat
posed by pandemic influenza. In the early phases of a pandemic, the only treatment …