Whole genome sequencing unlikely to be funded by government health plans
T Morris - Canadian Medical Association. Journal, 2018 - search.proquest.com
The findings of the Personal Genome Project (PGP) are ambiguous because they tell only
part of the story of genetic disease. 1 It is common to use the words “genetic” and “inherited” …
part of the story of genetic disease. 1 It is common to use the words “genetic” and “inherited” …
[PDF][PDF] Whole Genome Sequencing–a New Paradigm for Clinical Care?
R Trent - Medical World - wma.net
Human genetic disorders fall into three categories:(1) Somatic cell defects,(2) Mendelian
genetic disorders and (3) Complex genetic disorders (Table 1). The latter two involve the …
genetic disorders and (3) Complex genetic disorders (Table 1). The latter two involve the …
Whole-genome sequencing: a step closer to personalized medicine
B Pasche, D Absher - JAMA, 2011 - jamanetwork.com
THE PAST 60 YEARS HAVE WITNESSED REMARKABLE progress in genetics and
genomics from the descrip-tion of the DNA double helix by Watson and Crick1 to the release …
genomics from the descrip-tion of the DNA double helix by Watson and Crick1 to the release …
Whole genome sequencing--new opportunities for health care practice?
A de Jong, M Teeuw, AC Janssens - Nederlands Tijdschrift Voor …, 2010 - europepmc.org
In the near future it will probably be possible to unravel the DNA code of the human genome
for less than US $1,000 by means of'whole genome sequencing'(WGS). However, its …
for less than US $1,000 by means of'whole genome sequencing'(WGS). However, its …
The advent of personal genome sequencing
R Drmanac - Genetics in Medicine, 2011 - nature.com
Rapid technological advances are decreasing DNA sequencing costs and making it
practical to undertake complete human genome sequencing on a large scale for the first …
practical to undertake complete human genome sequencing on a large scale for the first …
Whole Genome Sequencing in the Clinical Laboratory
M Laurent, B Sickler, A Liao, P Cotter… - Journal of …, 2011 - ncbi.nlm.nih.gov
The advent of routine whole genome sequencing creates an opportunity to provide an
accurate, comprehensive and cost-effective catalogue of germline variation for an individual …
accurate, comprehensive and cost-effective catalogue of germline variation for an individual …
[HTML][HTML] Whole-genome sequencing in healthy people
NM Lindor, SN Thibodeau, W Burke - Mayo Clinic Proceedings, 2017 - Elsevier
Recent technological advances have radically changed genetic testing from an expensive
and burdensome undertaking to a rapid and less costly option for many purposes. The utility …
and burdensome undertaking to a rapid and less costly option for many purposes. The utility …
A one-page summary report of genome sequencing for the healthy adult
JL Vassy, HL McLaughlin, CA MacRae… - Public Health …, 2015 - karger.com
As genome sequencing technologies increasingly enter medical practice, genetics
laboratories must communicate sequencing results effectively to nongeneticist physicians …
laboratories must communicate sequencing results effectively to nongeneticist physicians …
Is gene discovery research or diagnosis?
ME Samuels, A Orr, DL Guernsey, K Dooley… - Genetics in …, 2008 - nature.com
The criteria that distinguish human genetic research from clinical molecular diagnosis are
frequently practical rather than theoretical. They are driven by the availability and costs of …
frequently practical rather than theoretical. They are driven by the availability and costs of …
Whole-genome sequencing: the new standard of care?
LR Brunham, MR Hayden - Science, 2012 - science.org
Rapid advances in DNA sequencing technology have made whole-genome sequencing
(WGS) both technically and economically feasible. WGS has been used with great effect in …
(WGS) both technically and economically feasible. WGS has been used with great effect in …