Purpose To update the 2003 American Society of Clinical Oncology technology assessment
on adjuvant use of aromatase inhibitors. Recommendations Based on results from multiple …

… The trend test statistic (ie, the change from one stratum to the next in the log of the event
RR) is then T/var(T), which has variance 1/var(T). Tests of whether two trends are the same …

For many decades, the dominant approach to making decisions about treatment in the
medical encounter has been one of paternalism. 1–7 In recent years this model has been …

In this paper we revisit and add elements to our earlier conceptual framework on shared
treatment decision-making within the context of different decision-making approaches in the …

… They would not add such treatment based on T size; lymphovascular invasion; or the
involvement of one to three lymph nodes in such patients. However, the Panel almost unanimously …

This review found that after mastectomy and axillary dissection, radiotherapy reduced both
recurrence and breast cancer mortality in women with one to three positive lymph nodes, …

Shared decision-making is increasingly advocated as an ideal model of treatment decision-making
in the medical encounter. To date, the concept has been rather poorly and loosely …

Background The recurrence score based on the 21-gene breast cancer assay predicts
chemotherapy benefit if it is high and a low risk of recurrence in the absence of chemotherapy if it …

Background Prior studies with the use of a prospective–retrospective design including
archival tumor samples have shown that gene-expression assays provide clinically useful …

Background The optimal fractionation schedule for whole-breast irradiation after breast-conserving
surgery is unknown. Methods We conducted a study to determine whether a …