[HTML][HTML] The role of inflammation in diabetes: current concepts and future perspectives

…, G Vogiatzi, S Papaioannou, S Deftereos… - European cardiology …, 2019 - ncbi.nlm.nih.gov
Diabetes is a complex metabolic disorder affecting the glucose status of the human body.
Chronic hyperglycaemia related to diabetes is associated with end organ failure. The clinical …

Thalassemia heart disease: a comparative evaluation of thalassemia major and thalassemia intermedia

A Aessopos, D Farmakis, S Deftereos, M Tsironi… - Chest, 2005 - Elsevier
Background Heart disease represents the main determinant of survival in β-thalassemia, but
its particular features in the two clinical forms of the disease, thalassemia major (TM) and …

Literature mining, ontologies and information visualization for drug repurposing

…, A Sharma, V Virvilis, S Deftereos… - Briefings in …, 2011 - academic.oup.com
The immense growth of MEDLINE coupled with the realization that a vast amount of biomedical
knowledge is recorded in free-text format, has led to the appearance of a large number …

Hypothyroidism is a risk factor for new-onset diabetes: a cohort study

N Gronich, SN Deftereos, I Lavi, AS Persidis… - Diabetes …, 2015 - Am Diabetes Assoc
OBJECTIVE To identify risk factors for the development of statin-associated diabetes mellitus
(DM). RESEARCH DESIGN AND METHODS The study was conducted in two phases. …

Drug repurposing and adverse event prediction using high‐throughput literature analysis

SN Deftereos, C Andronis, EJ Friedla… - … Systems Biology and …, 2011 - Wiley Online Library
Drug repurposing is the process of using existing drugs in indications other than the ones
they were originally designed for. It is an area of significant recent activity due to the mounting …

Technical guidelines for enhancing privacy and data protection in modern electronic medical environments

…, D Lekkas, S Deftereos - IEEE Transactions …, 2005 - ieeexplore.ieee.org
Raising awareness and providing guidance to on-line data protection is undoubtedly a crucial
issue worldwide. Equally important is the issue of applying privacy-related legislation in a …

Cardiovascular effects of splenomegaly and splenectomy in β-thalassemia

A Aessopos, D Farmakis, S Deftereos, M Tsironi… - Annals of …, 2005 - Springer
Splenomegaly is common in β-thalassemia, bearing some particular hemodynamic features,
while splenectomy is an established therapeutic intervention in these patients. Their effects, …

Literature analysis for systematic drug repurposing: a case study from Biovista

E Lekka, SN Deftereos, A Persidis, A Persidis… - Drug Discovery Today …, 2011 - Elsevier
Drug Repositioning (DR) has recently emerged as a complementary approach to classic
drug discovery aiming at challenging the limited productivity issues associated with the …

[PDF][PDF] Cardiovascular adaptation to chronic anemia in the elderly: an echocardiographic study.

A Aessopos, S Deftereos, D Farmakis… - Clinical & …, 2004 - epe.lac-bac.gc.ca
Methods: We studied 41 elderly patients (mean age 69.8 yr, standard deviation [SD] 3.9 yr)
suffering from chronic severe anemia (mean hemoglobin 6.3, SD 0.5 g/dL) with no history of …

From depression to neurodegeneration and heart failure: re-examining the potential of MAO inhibitors

SN Deftereos, E Dodou, C Andronis… - Expert Review of …, 2012 - Taylor & Francis
Initially introduced in the 1950s for treating depression, monoamine oxidase (MAO)
inhibitors were gradually abandoned, mainly owing to their potential for drug–drug and drug–food …