The hundred-dollar genome: a health care cart before the genomic horse

S Singh - Cmaj, 2018 - Can Med Assoc
The science of genetics is grounded in the principles of inheritance outlined over 150 years
ago. Almost 100 years later, the physical bases for these principles were articulated in the …

The Human Genome Project at 10 years: A teachable moment

JP Evans - Genetics in Medicine, 2010 - nature.com
It's now been 10 years since humans deciphered the digital code that, in a very real sense,
defines us as a species. It's hard to overestimate the significance of that achievement but …

[BOOK][B] Genomic medicine

AE Guttmacher, FS Collins, JM Drazen, E Zerhouni - 2004 - press.jhu.edu
" Fifteen years ago, many questioned the wisdom of sequencing the human genome. There
were concerns not only about the technical feasibility of such an effort, but also that its …

Roundtable: The Human Genome Project

MS Brown, FS COLLINS, JL Goldstein… - Issues in Science and …, 1993 - JSTOR
The mapping of the human genome, described as the most ambitious undertaking in the
history of biol-ogy, has the power to change our understanding of life at its most basic level …

Genomes for all

GM Church - Scientific American, 2006 - JSTOR
In 1984 and 1985, I was among a dozen or so researchers who proposed a Human Genome
Project (HGP) to read, for the first time, the entire instruction book for making and …

[HTML][HTML] Ten years on—the human genome and medicine

H Varmus - New England Journal of Medicine, 2010 - Mass Medical Soc
On a June day nearly 10 years ago, the leaders of the United States and the United
Kingdom, accompanied by the leaders of the public and private teams deciphering the …

The Personal Genome Project Canada: findings from whole genome sequences of the inaugural 56 participants

MS Reuter, S Walker, B Thiruvahindrapuram, J Whitney… - Cmaj, 2018 - Can Med Assoc
BACKGROUND: The Personal Genome Project Canada is a comprehensive public data
resource that integrates whole genome sequencing data and health information. We …

Complicated legacies: The human genome at 20

KM Jones, R Cook-Deegan, CN Rotimi, SL Callier… - Science, 2021 - science.org
Millions of people today have access to their personal genomic information. Direct-to-
consumer services and integration with other “big data” increasingly commoditize what was …

[BOOK][B] The $1,000 genome: the revolution in DNA sequencing and the new era of personalized medicine

K Davies - 2015 - books.google.com
Since the conclusion of the Human Genome Project in 2003, scientists have been racing
towards a grand goal: offering individuals a decoding of their complete genetic makeup for …

[PDF][PDF] The Human Genome Project

S Scherer, LC Tsui - CAN. J. POL'Y, 2001 - tcag.ca
ABSTRACT▶ We now have a draft sequence of the entire human genome and most of the
genes it encodes. Here we explain what the genome is, what it means to sequence it, outline …