Propoxyphene use and risk for hip fractures in older adults
SJ Kamal-Bahl, BC Stuart, MH Beers - The American journal of geriatric …, 2006 - Elsevier
BACKGROUND:: Published guidelines have identified propoxyphene as an inappropriate
medication for use in aged patients. It is no more effective than acetaminophen, yet has
been associated with the same adverse effects (AEs) associated with other opioid drugs. In
particular, its central nervous system-related AEs, dizziness and sedation, may increase the
risk for fracture resulting from falls in older adults. Nonetheless, US studies have reported
widespread use of propoxyphene in the elderly US population. OBJECTIVE:: The aim of this …
medication for use in aged patients. It is no more effective than acetaminophen, yet has
been associated with the same adverse effects (AEs) associated with other opioid drugs. In
particular, its central nervous system-related AEs, dizziness and sedation, may increase the
risk for fracture resulting from falls in older adults. Nonetheless, US studies have reported
widespread use of propoxyphene in the elderly US population. OBJECTIVE:: The aim of this …
