Background: Disturbance of the sleep–wake cycle is a characteristic of delirium. In addition,
changes in melatonin rhythm influence the circadian rhythm and are associated with delirium…

Importance Decision-making on management of proximal femoral fractures in frail patients
with limited life expectancy is challenging, but surgical overtreatment needs to be prevented. …

Background With an ageing population, older persons become a larger part of the hospital
population. The incidence of delirium is high in this group, and experiencing delirium has …

Background Although only 39 % of patients with wrist trauma have sustained a fracture, the
majority of patients is routinely referred for radiography. The purpose of this study was to …

Background In most hospitals, children with acute wrist trauma are routinely referred for
radiography. Objective To develop and validate a clinical decision rule to decide whether …

Introduction Surgery for proximal femoral fractures in the Netherlands is performed by
trauma surgeons, general surgeons and orthopaedic surgeons. The aim of this study was to …

Purpose While most patients with wrist trauma are routinely referred for radiography, around
50% of these radiographs show no fracture. To avoid unnecessary radiographs, the …

Background The Amsterdam Pediatric Wrist Rules have been developed and validated to
reduce wrist radiographs following wrist trauma in pediatric patients. However, the actual …

Background In the Netherlands about 18,000 procedures with implant removal are
performed annually following open or closed reduction and fixation of fractures, of which 30-80% …

Purpose To allow physicians to be more selective in their request for a radiograph of the wrist
and to potentially reduce costs, the Amsterdam Wrist Rules (AWR) have been developed, …