User profiles for Philip S. Wells

Philip Wells

University of Ottawa or Ottawa Hospital Research Institute
Verified email at toh.ca
Cited by 70259

[HTML][HTML] Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis

PS Wells, DR Anderson, M Rodger… - … England Journal of …, 2003 - Mass Medical Soc
Background Several diagnostic strategies using ultrasound imaging, measurement of D-dimer,
and assessment of clinical probability of disease have proved safe in patients with …

Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer

PS Wells, DR Anderson, M Rodger… - Thrombosis and …, 2000 - thieme-connect.com
We have previously demonstrated that a clinical model can be safely used in a management
strategy in patients with suspected pulmonary embolism (PE). We sought to simplify the …

Value of assessment of pretest probability of deep-vein thrombosis in clinical management

PS Wells, DR Anderson, J Bormanis, F Guy, M Mitchell… - The Lancet, 1997 - thelancet.com
Background When ultrasonography is used to investigate deep-vein thrombosis, serial
testing is recommended for those who test negative initially. Serial testing is inconvenient for …

Does this patient have deep vein thrombosis?

PS Wells, C Owen, S Doucette, D Fergusson, H Tran - Jama, 2006 - jamanetwork.com
ContextOutpatients with suspected deep vein thrombosis (DVT) have nonspecific signs and
symptoms. Missed DVT diagnosis may result in fatal pulmonary embolism. Since many …

Excluding pulmonary embolism at the bedside without diagnostic imaging: management of patients with suspected pulmonary embolism presenting to the emergency …

PS Wells, DR Anderson, M Rodger, I Stiell… - Annals of internal …, 2001 - acpjournals.org
Background: The limitations of the current diagnostic standard, ventilation-perfusion lung
scanning, complicate the management of patients with suspected pulmonary embolism. We …

Use of a clinical model for safe management of patients with suspected pulmonary embolism

PS Wells, JS Ginsberg, DR Anderson… - Annals of internal …, 1998 - acpjournals.org
Background: The low specificity of ventilation-perfusion lung scanning complicates the
management of patients with suspected pulmonary embolism. Objective: To determine the safety …

Antithrombotic therapy for VTE disease: antithrombotic therapy and prevention of thrombosis: American College of Chest Physicians evidence-based clinical practice …

…, H Bounameaux, SZ Goldhaber, ME Nelson, PS Wells… - Chest, 2012 - Elsevier
Background This article addresses the treatment of VTE disease. Methods We generated
strong (Grade 1) and weak (Grade 2) recommendations based on high-quality (Grade A), …

Further validation and simplification of the Wells clinical decision rule in pulmonary embolism

…, VE Gerdes, PM Bossuyt, PS Wells… - Thrombosis and …, 2008 - thieme-connect.com
The Wells rule is a widely applied clinical decision rule in the diagnostic work-up of patients
with suspected pulmonary embolism (PE).The objective of this study was to replicate, …

Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial

…, S Pleasance, C Skedgel, K O'Rouke, PS Wells - Jama, 2007 - jamanetwork.com
ContextVentilation-perfusion (/) lung scanning and computed tomographic pulmonary
angiography (CTPA) are widely used imaging procedures for the evaluation of patients with …

A novel and rapid whole-blood assay for D-dimer in patients with clinically suspected deep vein thrombosis

PS Wells, P Brill-Edwards, P Stevens, A Panju, A Patel… - Circulation, 1995 - Am Heart Assoc
Background The clinical utility of using a novel whole blood assay for D-dimer (SimpliRED),
alone or in combination with impedance plethysmography (IPG), was investigated in a two-…