“Bioactive compounds” are extranutritional constituents that typically occur in small quantities
in foods. They are being intensively studied to evaluate their effects on health. The impetus …

Since the first AHA Science Advisory “Fish Consumption, Fish Oil, Lipids, and Coronary Heart
Disease,” 1 important new findings, including evidence from randomized controlled trials (…

Poor diet quality is strongly associated with elevated risk of cardiovascular disease morbidity
and mortality. This scientific statement emphasizes the importance of dietary patterns …

Various organizations worldwide have made dietary recommendations for eicosapentaenoic
acid (EPA), docosahexaenoic acid (DHA), and fish intake that are primarily for coronary …

Dietary recommendations have been made for n−3 fatty acids, including α-linolenic acid (ALA),
eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) to achieve nutrient …

Multiple randomized controlled trials (RCTs) have assessed the effects of supplementation
with eicosapentaenoic acid plus docosahexaenoic acid (omega-3 polyunsaturated fatty acids…

Background— Poor lifestyle behaviors, including suboptimal diet, physical inactivity, and
tobacco use, are leading causes of preventable diseases globally. Although even modest …

In the United States, intake of n−3 fatty acids is ≈1.6 g/d (≈0.7% of energy), of which 1.4 g
is α-linolenic acid (ALA; 18:3) and 0.1–0.2 g is eicosapentaenoic acid (EPA; 20:5) and …

Background Low-fat diets increase plasma triacylglycerol and decrease HDL-cholesterol
concentrations, thereby potentially adversely affecting cardiovascular disease (CVD) risk. High–…

The purpose of this review is to summarize our current understanding of the cholesterolemic
effects of individual fatty acids. Although historically there has been great interest in the fatty …