Depression is widely viewed as a chronic and recurrent mental illness that carries a high
burden of illness, which is mostly related to a young age at onset and chronicity of illness. 1 …

Major depressive disorder is the leading cause of physical and mental disability worldwide,
affecting more than 264 million people. A disproportionate amount of the enormous …

Background: Many people with depression experience repeated episodes. Previous
research into the predictors of chronic depression has focused primarily on the clinical …

Objective: To determine the likelihood of antidepressant response in older adults with major
depression as a function of their prior antidepressant trials. Methods: 500 older adults with …

Background Major depressive disorder (MDD) is characterized by high relapse/recurrence
rates. Predicting individual patients' relapse/recurrence risk has proven hard, possibly due to …

Background Course of illness in major depression (MD) is highly varied, which might lead to
both under-and overtreatment if clinicians adhere to a'one-size-fits-all'approach. Novel …

It’s Time to Rethink How We Measure Remission from Depression | NEJM Catalyst Skip to
main content NEJM Catalyst homepage Advanced Search SEARCH JOURNAL View Current …

Objective: Depression is a disease with high recurrence rates. Identifying predictors of
recurrence and their relative importance in patients with recurrent depression is important for …

Objectives Many studies examined predictors of depressive relapse/recurrence but no
simple tool based on well-established risk factors is available that estimates the risk within …

Background Most patients who present with depression are treated in primary care by
general practitioners (GPs). Relapse of depression is common (at least 50% of patients …