Obesity and risk of vascular disease: importance of endothelium‐dependent vasoconstriction
Obesity has become a serious global health issue affecting both adults and children. Recent
devolopments in world demographics and declining health status of the world's population …
devolopments in world demographics and declining health status of the world's population …
Optimizing therapy to prevent avoidable hospital admissions in multimorbid older adults (OPERAM): cluster randomised controlled trial
…, Z Shen, S Marien, AJ Meinders, O Baretella… - bmj, 2021 - bmj.com
Objective To examine the effect of optimising drug treatment on drug related hospital
admissions in older adults with multimorbidity and polypharmacy admitted to hospital. Design …
admissions in older adults with multimorbidity and polypharmacy admitted to hospital. Design …
Dilation of epicardial coronary arteries by the G protein-coupled estrogen receptor agonists G-1 and ICI 182,780
Endogenous estrogens protect from coronary artery disease in premenopausal women, but
the mechanisms involved are only partly understood. This study investigated whether …
the mechanisms involved are only partly understood. This study investigated whether …
Association of diabetes with atrial fibrillation phenotype and cardiac and neurological comorbidities: Insights from the Swiss‐AF study
…, R Kobza, S Aeschbacher, O Baretella… - Journal of the …, 2021 - Am Heart Assoc
Background Diabetes is a major risk factor for atrial fibrillation (AF). However, it remains unclear
whether individual AF phenotype and related comorbidities differ between patients who …
whether individual AF phenotype and related comorbidities differ between patients who …
Association between diabetes overtreatment in older multimorbid patients and clinical outcomes: an ancillary European multicentre study
A Christiaens, O Baretella, C Del Giovane… - Age and …, 2023 - academic.oup.com
Background Diabetes overtreatment is a frequent and severe issue in multimorbid older
patients with type 2 diabetes (T2D). Objective This study aimed at assessing the association …
patients with type 2 diabetes (T2D). Objective This study aimed at assessing the association …
Alcohol consumption and risk of cardiovascular outcomes and bleeding in patients with established atrial fibrillation
…, M Coslovsky, M Kühne, N Rodondi, O Baretella… - Cmaj, 2021 - Can Med Assoc
BACKGROUND: Little is known about the association between alcohol consumption and risk
of cardiovascular events in patients with established atrial fibrillation (AF). The main aim of …
of cardiovascular events in patients with established atrial fibrillation (AF). The main aim of …
[HTML][HTML] The omega-3 fatty acid eicosapentaenoic acid (EPA) correlates inversely with ischemic brain infarcts in patients with atrial fibrillation
…, G Montrasio, S Aeschbacher, N Rodondi, O Baretella… - Nutrients, 2021 - mdpi.com
The omega-3 fatty acid (n-3 FA) eicosapentaenoic acid (EPA) reduces stroke in patients with
atherosclerotic cardiovascular disease. Whether EPA affects stroke or cerebral small vessel …
atherosclerotic cardiovascular disease. Whether EPA affects stroke or cerebral small vessel …
Acidosis prevents and alkalosis augments endothelium-dependent contractions in mouse arteries
O Baretella, A Xu, PM Vanhoutte - Pflügers Archiv-European Journal of …, 2014 - Springer
Abstract Changes in pH modulate the responsiveness of vascular smooth muscle cells to
vasoconstrictor stimuli, but their effect on endothelium-dependent responses is unknown. …
vasoconstrictor stimuli, but their effect on endothelium-dependent responses is unknown. …
No effect of levothyroxine on hemoglobin in older adults with subclinical hypothyroidism: pooled results from 2 randomized controlled trials
…, S Byrne, N Rodondi, O Baretella… - The Journal of …, 2022 - academic.oup.com
Context Subclinical thyroid dysfunction and anemia are common disorders, and both have
increasing prevalence with advancing age. Objective The aim of this study was to assess …
increasing prevalence with advancing age. Objective The aim of this study was to assess …
[HTML][HTML] Obesity and heterozygous endothelial overexpression of prepro-endothelin-1 modulate responsiveness of mouse main and segmental renal arteries to …
Aims Levels of the endothelium-derived peptide endothelin-1 (ET-1) are elevated in obese
humans, and ET-1 mediated vascular tone is increased. Renal arterial smooth muscle is …
humans, and ET-1 mediated vascular tone is increased. Renal arterial smooth muscle is …
