The Personal Genome Project Canada: findings from whole genome sequences of the inaugural 56 participants
MS Reuter, S Walker, B Thiruvahindrapuram, J Whitney… - Cmaj, 2018 - Can Med Assoc
BACKGROUND: The Personal Genome Project Canada is a comprehensive public data
resource that integrates whole genome sequencing data and health information. We …
resource that integrates whole genome sequencing data and health information. We …
Whole genome sequencing in the clinic: empowerment or too much information?
AJ Berberich, R Ho, RA Hegele - Cmaj, 2018 - Can Med Assoc
CMAJ| FEBRUARY 5, 2018| VOLUME 190| ISSUE 5 E125 definitive than those offered by
direct-to-consumer genetic testing services, which use older technology and detect only a …
direct-to-consumer genetic testing services, which use older technology and detect only a …
Personal Genome Project UK (PGP-UK): a research and citizen science hybrid project in support of personalized medicine
BMC medical genomics, 2018 - Springer
Background Molecular analyses such as whole-genome sequencing have become routine
and are expected to be transformational for future healthcare and lifestyle decisions …
and are expected to be transformational for future healthcare and lifestyle decisions …
Psychological and behavioural impact of returning personal results from whole-genome sequencing: the HealthSeq project
Providing ostensibly healthy individuals with personal results from whole-genome
sequencing could lead to improved health and well-being via enhanced disease risk …
sequencing could lead to improved health and well-being via enhanced disease risk …
Potential research participants support the return of raw sequence data
Health-related results that are discovered in the process of genomic research should only be
returned to research participants after being clinically validated and then delivered and …
returned to research participants after being clinically validated and then delivered and …
Systematic analysis and functional annotation of variations in the genome of an Indian individual
Whole genome sequencing of personal genomes has revealed a large repertoire of
genomic variations and has provided a rich template for identification of common and rare …
genomic variations and has provided a rich template for identification of common and rare …
A public resource facilitating clinical use of genomes
Rapid advances in DNA sequencing promise to enable new diagnostics and individualized
therapies. Achieving personalized medicine, however, will require extensive research on …
therapies. Achieving personalized medicine, however, will require extensive research on …
Exploring broad consent in the context of the 100,000 Genomes Project: a mixed methods study
LM Ballard, RH Horton, S Dheensa… - European journal of …, 2020 - nature.com
Abstract The 100,000 Genomes Project (100kGP)—a hybrid clinical-research initiative—was
set up to analyse whole-genome sequences (WGS) from patients living with a rare disease …
set up to analyse whole-genome sequences (WGS) from patients living with a rare disease …
Clinical interpretation and implications of whole-genome sequencing
Importance Whole-genome sequencing (WGS) is increasingly applied in clinical medicine
and is expected to uncover clinically significant findings regardless of sequencing indication …
and is expected to uncover clinically significant findings regardless of sequencing indication …
Genomic data in the All of Us research program
Comprehensively mapping the genetic basis of human disease across diverse individuals is
a longstanding goal for the field of human genetics. 1-4 The All of Us Research Program is a …
a longstanding goal for the field of human genetics. 1-4 The All of Us Research Program is a …
