Posttraumatic elbow stiffness remains a common and challenging clinical problem. In the
setting of a congruent articular surface, the joint capsule is regarded as the major motion-…

Alveolar soft part sarcoma (ASPS), a deadly soft tissue malignancy with a predilection for
adolescents and young adults, associates consistently with t(X;17) translocations that generate …

Objectives Using a rabbit model of post-traumatic joint contractures, we investigated
whether treatment with a mast cell stabilizer after joint injury would lessen the molecular …

Background: The propensity of joints to become stiff after trauma is widely appreciated, and
the joint capsule is commonly recognized as the major motion-limiting anatomical structure. …

Significance: The pathogenesis of fibrogenic wound and connective tissue healing is complex
and incompletely understood. Common observations across a vast array of human and …

The genetics of Ewing sarcoma development remain obscure. The incidence of Ewing sarcoma
is ten-fold less in Africans as compared to Europeans, irrespective of geographic location…

Background and Objectives Given advances in therapies, endoprosthetic reconstruction (EPR)
in metastatic bone disease (MBD) may be increasingly indicated. The objectives were to …

Background A growing collection of retrospective studies have suggested that TP53 mutations
and/or CDKN2A deletions have prognostic significance in Ewing sarcoma. We sought to …

Background The genetics involved in Ewing sarcoma susceptibility and prognosis are poorly
understood. EWS/FLI and related EWS/ETS chimeras upregulate numerous gene targets …

Synovial sarcomas are aggressive soft-tissue malignancies that express chromosomal
translocation-generated fusion genes, SS18-SSX1 or SS18-SSX2 in most cases. Here, we report …