Changes in endoplasmic reticulum luminal environment affect cell sensitivity to apoptosis

…, E Bossy-Wetzel, K Burns, MP Fadel… - The Journal of cell …, 2000 - rupress.org
To test the role of ER luminal environment in apoptosis, we generated HeLa cell lines
inducible with respect to calreticulin and calnexin and investigated their sensitivity to drug-…

Disc1 point mutations in mice affect development of the cerebral cortex

FHF Lee, MP Fadel, K Preston-Maher… - Journal of …, 2011 - Soc Neuroscience
Disrupted-in-Schizophrenia 1 (DISC1) is a strong candidate gene for schizophrenia and
other mental disorders. DISC1 regulates neurodevelopmental processes including …

Calreticulin affects focal contact-dependent but not close contact-dependent cell-substratum adhesion

MP Fadel, E Dziak, CM Lo, J Ferrier, N Mesaeli… - Journal of Biological …, 1999 - ASBMB
We used two cell lines expressing fast (RPE fast ) and slow (RPE slow ) attachment kinetics
to investigate mechanisms of cell-substratum adhesion. We show that the abundance of a …

Calreticulin affects β-catenin-associated pathways

MP Fadel, M Szewczenko-Pawlikowski… - Journal of Biological …, 2001 - ASBMB
Calreticulin, a Ca 2+ storage protein and chaperone in the endoplasmic reticulum, also
modulates cell adhesiveness. Overexpression of calreticulin correlates with (i) increased cell …

Calreticulin affects fibronectin-based cell-substratum adhesion via the regulation of c-Src activity

S Papp, MP Fadel, H Kim, CA McCulloch… - Journal of biological …, 2007 - ASBMB
Calreticulin is an endoplasmic reticulum Ca 2+ -storage protein, which influences gene
expression and cell adhesion. In this study, we show that calreticulin induces fibronectin gene …

Ethical tensions in the treatment of youth with severe anorexia nervosa

…, L Fleming, V Rawal, MP Fadel… - The Lancet Child & …, 2023 - thelancet.com
Treatment of anorexia nervosa poses a moral quandary for clinicians, particularly in paediatrics.
The challenges of appropriately individualising treatment while balancing prospective …

Pax3 induces cell aggregation and regulates phenotypic mesenchymal-epithelial interconversion

ON Wiggan, MP Fadel, PA Hamel - Journal of cell science, 2002 - journals.biologists.com
Paired box-containing transcription factors play fundamental roles in pattern formation
during embryonic development of diverse organisms ranging from Drosophila to mammals. …

Mgat5 modulates the effect of early life stress on adult behavior and physical health in mice

L Feldcamp, JS Doucet, J Pawling, MP Fadel… - Behavioural brain …, 2016 - Elsevier
… Mgat5 −/− mice generally had more complex dendritic trees than wild-type mice (p = 0.016
comparing genotypes in both MS and NR groups). However, this genotype effect appears to …

Dissecting focal adhesions in cells differentially expressing calreticulin: a microscopy study

S Papp, MP Fadel, M Opas - Biology of the Cell, 2007 - Wiley Online Library
Background information. Our previous studies have shown that calreticulin, a Ca 2+ ‐binding
chaperone located in the endoplasmic reticulum, affects cell—substratum adhesions via …

Influence of the Al content on the structure, optoelectronic properties and electronic structure of AZO transparent electrodes deposited by HiPIMS for solar energy …

C Fadel - 2022 - publikationen.sulb.uni-saarland.de
THÈSE Christy FADEL Influence of the Al content on the structure, optoelectronic properties …
sur des hétérojonctions de type n-ZnO/p-Cu2O en combinant la pulvérisation cathodique …