A recent monograph by Hurlbert raised several problems concerning the appropriate design
of sampling programs to assess the impact upon the abundance of biological populations of…

INTRODUCTION Most cancers are recognized and attacked by the immune system but can
progress owing to tumor-mediated immunosuppression and immune evasion mechanisms. …

INTRODUCTION More than 50% of patients treated with chimeric antigen receptor (CAR)–T
cells for B cell malignancies develop progressive disease after CAR therapy, and these …

… Parker is Chair and Professor of the Department of Informatics and Computer Science at
Idaho State University. Parker’s research interests include eGovernment and the elderly, …

The idea that" structure mediates function" is a conceptual thread that has woven through
biological research for decades. The molecules in biological superstructures such as …

1 Why an electrostatic precipitator? Page 1 1 Why an electrostatic precipitator? KR PARKER
1.1 Introduction Stricter environmental legislation in many countries is producing ever…

CD19-directed immunotherapies are clinically effective for treating B cell malignancies but
also cause a high incidence of neurotoxicity. A subset of patients treated with chimeric …

We introduce APEX-seq, a method for RNA sequencing based on direct proximity labeling
of RNA using the peroxidase enzyme APEX2. APEX-seq in nine distinct subcellular locales …

Regulatable CAR platforms could circumvent toxicities associated with CAR-T therapy, but
existing systems have shortcomings including leakiness and attenuated activity. Here, we …

Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally
that could serve as immune targets. We developed T cells expressing chimeric antigen …