… in human Down syndrome tissues has not been reported. … In Down syndrome, there is a
primary transcriptional effect of … changes that may underlie the Down syndrome phenotypes. …

… Down syndrome (DS) is the most common cause of … Down syndrome disintegrative disorder
(DSDD), Down syndrome regression disorder (DSRD) and unexplained regression in Down …

… risk of Down syndrome. If a thickened nuchal fold is used to screen for Down syndrome, 15
893 … need to be screened for each case of Down syndrome identified. For each of the other 6 …

… The best-studied member of the DYRK family is DYRK1A, owing to its role in the pathology
of Down syndrome and the early onset of neurodegeneration. DYRK members have been …

In recent pediatric trials of acute myeloid leukemia (AML), children with Down syndrome (DS)
have had significantly more megakaryoblastic leukemia and have experienced better …

… Participants were identified via services for people with intellectual disabilities in England
and Scotland, through the Down Syndrome Association or following responses to our Web site…

We analyze the present day structure and assembly history of a high-resolution hydrodynamic
simulation of the formation of a Milky-Way-(MW)-like disk galaxy, from the" Eris" simulation …

… ‘Top-down’ interrogation of whole proteins can overcome these problems for individual
proteins 4,5 , but has not been achieved … We dedicate this work in memory of Jonathan Widom. …

… with Down syndrome … Down syndrome. This article reports the text responses collected in
the survey and is intended as a step towards understanding the difficulties children with Down …

… Judged over two centuries, Jonathan Edwards stands forth as one of America's great original
… concludes that Edwards's work seems virtually inexhaustible and impossible to pin down. …