BACKGROUND: Trazodone is increasingly prescribed for behavioural and psychological
symptoms of dementia, but little is known about its risk of harm. Our objective was to …

Background In vitro and animal studies have suggested that trazodone, a licensed
antidepressant, may protect against dementia. However, no studies have been conducted to …

Objectives To investigate whether trazodone is being initiated in lieu of antipsychotics
following antipsychotic reduction efforts, this study described changes in medication …

BACKGROUND: Atypical antipsychotic agents are extensively prescribed in the elderly to
treat various behavioral and psychiatric disorders. Past literature has documented an …

Background There is growing evidence of harm associated with trazodone and
nonbenzodiazepine sedative hypnotics (eg, zopiclone); however, their comparative risk of …

Background Antidepressants are one of the most commonly prescribed medications in
young and middle-aged adults, but there is relatively little information on their safety across …

Objectives Evidence in mouse models has found that the antidepressant trazodone may be
protective against neurodegeneration. We therefore aimed to compare cognitive decline of …

Objectives To evaluate whether risk of fall‐related injuries differs between nursing home
(NH) residents newly dispensed low‐dose trazodone and those newly dispensed …

Background Benzodiazepine medications have well-documented side effects, and their
prescription rates in older adults have been declining. Trazodone and quetiapine are …

Background Antipsychotics, especially atypical agents, are widely used in the elderly
population to treat behavioural and psychiatric symptoms. Very few studies have compared …