Objectives: TrialNet’s goal to test preventions for type 1 diabetes has created an opportunity
to gain new insights into the natural history of pre‐type 1 diabetes. The TrialNet Natural …

OBJECTIVE—There is little information regarding the pattern of metabolic deterioration before
the onset of type 1 diabetes. The goal of this study was to utilize data from the Diabetes …

Importance Early exposure to complex dietary proteins may increase the risk of type 1 diabetes
in children with genetic disease susceptibility. There are no intact proteins in extensively …

Background: Statin-related myalgia is difficult to distinguish from other conditions causing
myalgia and may often lead to statin discontinuation. Objective: To compare the effect of statin …

Objective: To compare outcomes between groups of patients with irreversible chronic airflow
limitation given theophylline by n of 1 trials or standard practice. Design: Randomised …

OBJECTIVE We assessed whether a risk score that incorporates levels of multiple islet
autoantibodies could enhance the prediction of type 1 diabetes (T1D). RESEARCH DESIGN AND …

Background: Waits for elective total hip arthroplasty for osteoarthritis are common in publicly
funded health care systems, but they may lead to poorer postoperative outcomes and loss of …

Objective –To describe the natural course of clinical remission in insulin-dependent diabetes
mellitus (IDDM) when insulin dose is minimized without loss of target glycemia and to …

OBJECTIVE—The accurate prediction of type 1 diabetes is essential for appropriately identifying
prevention trial participants. Thus, we have developed a risk score for the prediction of …

Objective To update the evidence-based recommendations for the prevention and treatment
of hypertension in adults for 2010. Options and outcomes For lifestyle and pharmacological …